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Table 3 Ordinal susceptibility scores for antimicrobial-organism pairs included in the spectrum score

From: Description and validation of a spectrum score method to measure antimicrobial de-escalation in healthcare associated pneumonia from electronic medical records data

  Anti-MRSA* βL- Inhibitors** Carbapenems & aztreonam*** Cephalosporins****
  Vanc Lzld Tig Dapto Ceftar Pip/Taz Tic/Clav Amino-BLI PSA Carb Erta Aztr 1st Gen Ceph 2nd Gen Ceph 3rd Gen Ceph PSA Ceph
Gram positive organisms                
Staphylococcus aureus 0I
Streptococcus pneumoniae 0I
Enterococcus faecalis 0I
Enterococcus faecium 0I
Gram negative organisms                
Escherichia coli 0I 0I 0I
Klebsiella spp. 0I 0I 0I
OtherEnterobacteriaceae 0I 0I 0I
Enterobacter spp. 0I 0I 0I
Citrobacter spp. 0I 0I 0I
Serratia spp. 0I 0I 0I
Morganella spp. 0I 0I 0I
Proteus spp. 0I 0I 0I
Providencia spp. 0I 0I 0I 0
Pseudomonas aeruginosa 0I 0I 0I 0I 0I 4Ϯ 0I 0I 0I
Acinetobacter spp. 0I 0I 0I
Stenotrophomonas spp. 0I 0I 0I 0I
Haemophilus influenzae 0I 0I
Bacteroides spp. 0I 0I 0I 0I 0I 0I 0I
Other organisms                
Atypical organisms 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I
Legionella spp. 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I
Mycoplasma spp. 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I 0I
  Penicillins***** Miscellaneous******
  Amino PCN Semi Synth PCN PSAFQ NON-PSAFQ Amik Gent or Tobra Macro Clinda Tetra TMP/SMX Metro Colistin    
Gram positive organisms                
Staphylococcus aureus 0I    
Streptococcus pneumoniae 0I    
Enterococcus faecalis 0I 0I 0I    
Enterococcus faecium 0I 0I 0I    
Gram negative organisms                
Escherichia coli 0I 0I 0I 0I    
Klebsiella spp. 0I 0I 0I 0I    
OtherEnterobacteriaceae 0I 0I 0I 0I    
Enterobacter spp. 0I 0I 0I 0I    
Citrobacter spp. 0I 0I 0I 0I    
Serratia spp. 0I 0I 0I 0I    
Morganella spp. 0I 0I 0I 0I    
Proteus spp. 0I 0I 0I 0I    
Providencia spp. 0I 0I 0I 0I    
Pseudomonas aeruginosa 0I 0I 0I 0I 0I 0I 0I    
Acinetobacter spp. 0I 0I 0I 0I    
Stenotrophomonas spp. 0I 0I 0I 0I    
Haemophilus influenzae 0I 0I    
Bacteroides spp. 0I 0I 0I 0I    
Other organisms                
Atypical organisms 0I 0I 0I 0I    
Legionella spp. 0I 0I 0I 0I    
Mycoplasma spp. 0I 0I 0I 0I    
  1. Special Notations:
  2. Ϯ VA susceptibility data.
  3. I No intrinsic activity.
  4. Ψ Investigator opinion.
  5. Ω Limited VA susceptibility data.
  6. ¥ Expert rule.
  7. Κ Literature based.
  8. Abbreviations:
  9. *Anti-MRSA: Vanc = vancomycin; Lzld = linezolid; Tig = tigecycline; Dapto = daptomycin, Ceftar = ceftaroline.
  10. **βL- Inhibitors: Pip/Taz = piperacillin/tazobactam; Tic/Clav = ticarcillin/clavulanate; AminoBLI = ampicillin/sulbactam, amoxicillin/clavulanate.
  11. ***Carbapenems and Aztreonam: PSACarba = imipenem, meropenem, Erta = ertapenem, Aztr = aztreonam.
  12. ****Cephalosporins: 1st Gen Ceph. = cefazolin, cephalexin; 2nd Gen Ceph = cefuroxime; 3rd Gen Ceph = ceftriaxone, cefotaxime, cefpodoxime; PSACeph = cefepime, ceftazidime.
  13. *****Penicllins: AminoPCN = ampicillin, amoxicillin, penicillin; SemiSynthPCN = oxacillin, nafcillin.
  14. ******Miscellaneous: PSAFQ = ciprofloxacin or levofloxacin; NONPSAFQ = moxifloxacin, gemifloxacin; Amik = Amikacin; Gent or Tobra = gentamicin, tobramycin; Macro = erythromycin, azithromycin, clarithromycin; Clinda = clindamycin; Tetra = tetracycline, doxycycline; TMP/SMX = trimethoprim/sulfamethoxazole; Metro = metronidazole; Colistin = colistin.