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Table 2 Characteristics of the 1,704 vaccinated students stratified by age at vaccination

From: The long-term immunogenicity of recombinant hepatitis B virus (HBV) vaccine: contribution of universal HBV vaccination in Italy

  Vaccinated in infancy Vaccinated at 12 years old p
N° of students 588 1,116  
Age, years 21.5 ± 0.9 27.9 ± 4.4 0.000
Females 421 (72) 613 (55) 0.000
Place of birth: Italy 584 (99.5) 1101 (99) n.s.
Elsewhere 4 (0.5) 15 (1)  
Attending: School of medicine 33 (6) 492 (44) 0.000*
Healthcare profession school 555 (94) 274 (24.7)
Postgraduate medical school 0 350 (31.3)
Years from vaccination 21.5 ± 0.9 15.6 ± 3.2 0.000
Students with HBsAb < 10 IU/L 135 (23) 135 (12.1) 0.000
Students with HBsAb 10–400 IU/L 396 (67.3) 591 (53) 0.000
Genometric mean, IU/L 30.4 59.6 0.000**
Students with HBsAb >400 IU/L 57 (9.7) 390 (34.9) 0.000
Students with HBsAb <10 IU/L: Female 91/421 (21.6) 67/613 (11) n.s.
Male 44/167 (26.5) 68/503 (13.5)  
Vaccinated 1991–1995 135/588 (23) 13/202 (6.4) 0.000
Vaccinated 1996–2002 - 122/914 (13.3) -
  1. *Healthcare profession school students vs. all medical school students (graduate + postgraduate).
  2. **Mann–Whitney Test.
  3. Continuous variables are given as mean ± SD; categorical variables are given as n° (%).