Table 2 Univariate and multivariate† analysis of risk factors for enterococcal bloodstream infection among febrile children admitted to Muhimbili National Hospital (n = 1828)*

Neonate

28.2% (11/39)

29.3 (524/1789)

0.9 (0.47-1.92) 0.883

0.4 (0.14-0.98) 0.046

^‡g

Prematurity

9.1 (3/33)

3.2 (51/1570)

3.0 (0.88 - 10.08) 0.079

4.4 (1.06-18.1) 0.041

4.7 (1.19-18.8) 0.019

Male sex

61.5 (24/39)

55.4 (992/1789)

1.3 (0.67 - 2.47) 0.450

^‡e

2.9 (1.03-7.91) 0.043

Hospital acquired infection^#

48.7 (19/39)

33.2 (594/1789)

1.9 (1.01 - 3.61) 0.046

2.0 (0.96– 4.00) 0.066

1.8 (0.73-4.29) 0.209

Antibiotic use before blood culture

66.7 (26/39)

57.0 (1020/1789)

1.5 (0.77 – 2.95) 0.231

^‡c

^‡b

Cephalosporin use before blood culture

5.1 (2/39)

4.0% (71/1789)

1.3 (0.31 – 5.53) 0.715

^‡a

^‡c

Diagnoses

Malnutrition

21.2 (7/33)

15.4 (241/1570)

1.5 (0.64 - 3.46) 0.360

^‡f

3.7 (1.24-11.28) 0.019

HIV infection

13.0 (3/23)

18.8 (173/919)

0.6 (0.19 – 2.20) 0.486

§

0.5 (0.14-2.04) 0.363^§

Urinary tract infection

12.1% (4/33)

11.4% (179/1570)

1.1 (0.37- 3.08) 0.898

^‡b

^‡a

Pneumonia

21.2% (7/33)

20.1% (315/1570)

1.1 (0.46- 2.49) 0.871

^‡d

^‡e

Sepsis with unknown focus

45.5% (15/33)

29.4% (462/1570)

2.0 (1.00- 4.00) 0.050

2.9 (1.36-6.20) 0.006

2.6 (1.06-6.55) 0.037

Congenital heart disease

6.1% (2/33)

2.3% (36/1570)

2.7 (0.63- 11.93) 0.177

^‡g

^‡d

Acute watery diarrhoea

9.1 (3/33)

21.8 (343/1570)

0.4 (0.11 - 1.18) 0.091

0.3 (0.09-1.07) 0.065

^‡f