Figure 4

Differential vaccination kinetics and mucosal IgA induction. Mice were immunised intranasally with 10 μg of H1N1 mixed with 100 μg of mannan either on days 0, 10 and 17 with lung washes collected on day 22, or on days 0, 14 and 28 with lung washes collected on day 32. The amounts of anti-H1N1 IgA in the lung washes of individual mice were determined by ELISA.