Figure 2
From: Expression of inhibitory regulators of innate immunity in patients with active tuberculosis
SIGIRR during active pulmonary tuberculosis. (A) SIGIRR mRNA in PBMCs. (B) SIGIRR surface expression measured on CD4 and CD8 positive lymphocytes and CD14 positive monocytes (representative histograms). FMO, fluorescence minus one. (C) Idem for individual subjects (mean channel fluorescence intensity, MFI). (D) SIGIRR mRNA in alveolar macrophages (AM) of TB patients originating from the TB infected lung (open squares) or contralateral lung (closed squares). Depicted mRNAs are normalized to the house keeping gene β2-microglobulin. Depicted are dot plots with medians; open dots: TB patients, closed dots: healthy donors.