Table 3 Most frequent antibiotics used as initial therapy (monotherapy and combinations)
Definition 1 | Definition 2 | |||
|---|---|---|---|---|
Antibiotic, n (%) | Early responders | Not-early responders | Early responders | Not-early responders |
n = 363 | n = 237 | n = 417 | n = 173 | |
Empiric treatment | 327 (90.1) | 174 (73.4) | 368 (88.2) | 126 (72.8) |
Amoxicillin–clavulanate | 66 (18.2) | 29 (12.2) | 70 (16.8) | 24 (13.9) |
Piperacillin–tazobactam | 20 (5.5) | 20 (8.4) | 24 (5.8) | 16 (9.2) |
Ampicillin–sulbactam | 25 (6.9) | 47 (19.8) | 30 (7.2) | 42 (24.3) |
Cloxacillin | 16 (4.4) | 4 (1.7) | 18 (4.3) | 1 (0.6) |
Clindamycin | 14 (3.9) | 3 (1.3) | 15 (3.6) | 0 (0) |
Penicillins or combinations + fluoroquinolone | 11 (3.0) | 6 (2.5) | 12 (2.9) | 5 (2.9) |
Cefuroxime | 11 (3.0) | 5 (2.1) | 14 (3.4) | 2 (1.2) |
Fluoroquinolone | 6 (1.7) | 4 (1.7) | 6 (1.4) | 4 (2.3) |
Daptomycin | 11 (3.0) | 4 (1.7) | 11 (2.6) | 4 (2.3) |
Carbapenem | 9 (2.5) | 9 (3.8) | 10 (2.4) | 7 (4.0) |