Table 2 Clinical characteristics of 150 patients by final clinical classification
From: Prospective evaluation of GeneXpert for the diagnosis of HIV- negative pediatric TB cases
Total | Confirmed TB | Probable TB | Possible TB | TB unlikely | Not TB | |
|---|---|---|---|---|---|---|
N = 150 (%) | N = 38 (%) | N = 60 (%) | N = 33 (%) | N = 17 (%) | N = 2 (%) | |
History of illness (days) Median [IQR] | 30[6.45-90] | 30[6.4-94.5] | 30[8–90] | 17[6.6-72] | 30[2–60] | 30[30–30] |
Fever (>38°C) | P = 0.038 | |||||
≥1 week | 82 (54.7) | 22 (58.0) | 39 (65.0) | 15 (45.5) | 5 (29.4) | 1 (50) |
<1 week | 42 (28) | 8 (21.0) | 14 (23.3) | 14 (42.4) | 6 (35.3) | 0 (0) |
No fever | 26 (17.33) | 8 (21.0) | 7 (11.7) | 4 (12.1) | 6 (35.3) | 1(50) |
Persistent cough | P = 0.340 | |||||
Yes | 119 (79.3) | 30 (79.0) | 53 (88.3) | 23 (70.0) | 11 (64.7) | 2 (100) |
No | 31 (20.7) | 8 (21.0) | 7 (11.7) | 10 (30.0) | 6 (35.3) | 0 (0) |
Night sweats | P = 0.825 | |||||
Yes | 102 (68.0) | 21 (55.3) | 44 (73.3) | 25 (75.8) | 10 (58.8) | 2 (100) |
No | 48 (32.0) | 17 (44.7) | 16 (26.7) | 8 (24.2) | 7 (41.2) | 0 (0) |
Weight loss | P = 0.763 | |||||
Yes | 64 (42.7) | 17 (44.7) | 28 (46.7) | 12 (36.4) | 6 (35.5) | 2 (100) |
No | 86 (57.3) | 21 (55.3) | 32 (53.3) | 21 (63.6) | 11 (64.7) | 0 (0) |
Failure to thrive | P =0.378 | |||||
Yes | 61 (40.7) | 8 (21.0) | 30 (50.0) | 13 (39.4) | 8 (47.1) | 2 (100) |
No | 89 (59.3) | 30 (79.0) | 30 (50.0) | 20 (60.6) | 9 (52.9) | 0 (0) |
Reduced playfulness | P = 0.969 | |||||
Yes | 44 (29.3) | 9 (23.7) | 18 (30.0) | 12 (36.4) | 4 (23.5) | 1 (50) |
No | 106 (70.7) | 29 (76.3) | 42 (70.0) | 21 (63.6) | 13 (76.5) | 1 (50) |
Lymphadenopathy | P = 0.910 | |||||
Yes | 21 (14.0) | 9 (23.7) | 6 (10.0) | 4 (12.1) | 1 (5.9) | 1 (50) |
No | 129 (86.0) | 29 (76.3) | 54 (90.0) | 29 (87.9) | 16 (94.1) | 1 (50) |
Chest X ray | P = 0.060 | |||||
Consistent with TB | 143 (95.3) | 37 (97.4) | 60 (100) | 30 (90.9) | 14 (82.4) | 2 (100) |
Not consistent with TB | 5 (3.33) | 0 (0) | 0 (0) | 3 (9.1) | 2 (11.8) | 0 |
Unclear | 2 (1.3) | 1 (2.6) | 0 (0) | 0 (0) | 1 (5.2) | 0 |
TST | P = 0.3171 | |||||
<5 mm | 81 (73.0) | 15 (60.0) | 32 (66.7) | 29 (87.9) | 5 (100) | 0 |
≥5 mm - < 10 mm | 17 (15.3) | 5 (20.0) | 8 (16.7) | 4 (12.1) | 0 | 0 |
≥10 mm | 13 (11.7) | 5 (20) | 8 (16.7) | 0 | 0 | 0 |
Not done | 39 (26.0) | 13 (34.2) | 12 (20.0) | 0 | 12 (70.6) | 2 (100) |