| Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Variable | HR (95% CI) | Pvalue | Adjusted HR (95% CI) | Pvalue |
Neutropenia at the onset of BSI (<500/mm3) | 5.87 (0.784-44.037) | 0.085 | Â | Â |
Severe neutropenia at the onset of BSI (<100/mm3) | 3.47 (1.008-11.954) | 0.048 | 5.24 (1.411-19.493) | 0.013 |
Duration of neutropenia >21Â days | 3.29 (0.978-11.072) | 0.054 | Â | Â |
Hospital stay >30Â days | 1.44 (0.586-3.531) | 0.428 | Â | Â |
SAPS II >40 | 3.14 (1.265-7.783) | 0.003 | Â | Â |
Source of infection | Â | Â | Â | Â |
 Pneumonia | 4.27 (1.687-10.816) | 0.002 | 6.05 (2.247-16.291) | <0.001 |
 Catheter | 0.03 (0.000-1.817) | 0.093 |  |  |
Polymicrobial BSI | 1.43 (0.570-3.603) | 0.444 | Â | Â |
Shock | 3.09 (1.245-7.666) | 0.015 | 3.15 (1.231-8.032) | 0.017 |