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Table 2 Scenarios in the univariate and two-way sensitivity analysis

From: Modelling the return on investment of preventively vaccinating healthcare workers against pertussis

Nr. Scenarios Range for sensitivity analysis Source
1 Base case   
2 Average working days for nurses per week 3-5 −1 day and + 1 day
3 Average length of stay of neonates in neonatology ward 7-21 0.5 and 1.5 × base case
4 Length of patient restriction uptake on the neonatology ward (in days) 5-15 0.5 and 1.5 × base case
5 Average number of nurses & assistant working/day in the neonatology ward 20-40 0.5 and 1.5 × base case
6 Average number of consultant working/day in the neonatology ward 5-15 0.5 and 1.5 × base case
7 Number of staff members not able to work for 3 days after performing the PCR test 0-10 Assumed
8 Average number of new personnel in neonatology ward /year (in %) 5-15 0.5 and 1.5 × base case
9 No reduced working hours for nurses, neonatologists and other HCW due to ward closure 0 Assumed
10 Vaccine price €18,30 [17]
11 Costs considered in the ROI - only direct control costs €11.464 Assumed
12 Undiscounted outbreak and vaccination costs with 2 outbreaks in 10 years 0% Assumed
13 Discounted outbreak and vaccination costs with 1 outbreak in 10 years 4% [15]
14 Discounted outbreak and vaccination costs with 2 outbreaks in 10 years 4% [15]
15 Undiscounted outbreak and vaccination costs with 1 outbreak in 20 years 0% Assumed
16 Discounted outbreak and vaccination costs with 1 outbreak in 20 years 4% [15]
17 Smaller neonatology ward (HCW × 0,50 and ward occupation ×0,50) 0,50 Assumed
18 Bigger neonatology ward (HCW × 1,50 and ward occupation ×1,50) 1,50 Assumed
19 Length of patient restriction uptake on the neonatology ward (5 days) and average length of stay of neonates in neonatology ward (14 days) 5 14 Assumed