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Table 2 Scenarios in the univariate and two-way sensitivity analysis

From: Modelling the return on investment of preventively vaccinating healthcare workers against pertussis

Nr.

Scenarios

Range for sensitivity analysis

Source

1

Base case

  

2

Average working days for nurses per week

3-5

−1 day and + 1 day

3

Average length of stay of neonates in neonatology ward

7-21

0.5 and 1.5 × base case

4

Length of patient restriction uptake on the neonatology ward (in days)

5-15

0.5 and 1.5 × base case

5

Average number of nurses & assistant working/day in the neonatology ward

20-40

0.5 and 1.5 × base case

6

Average number of consultant working/day in the neonatology ward

5-15

0.5 and 1.5 × base case

7

Number of staff members not able to work for 3 days after performing the PCR test

0-10

Assumed

8

Average number of new personnel in neonatology ward /year (in %)

5-15

0.5 and 1.5 × base case

9

No reduced working hours for nurses, neonatologists and other HCW due to ward closure

0

Assumed

10

Vaccine price

€18,30

[17]

11

Costs considered in the ROI - only direct control costs

€11.464

Assumed

12

Undiscounted outbreak and vaccination costs with 2 outbreaks in 10 years

0%

Assumed

13

Discounted outbreak and vaccination costs with 1 outbreak in 10 years

4%

[15]

14

Discounted outbreak and vaccination costs with 2 outbreaks in 10 years

4%

[15]

15

Undiscounted outbreak and vaccination costs with 1 outbreak in 20 years

0%

Assumed

16

Discounted outbreak and vaccination costs with 1 outbreak in 20 years

4%

[15]

17

Smaller neonatology ward (HCW × 0,50 and ward occupation ×0,50)

0,50

Assumed

18

Bigger neonatology ward (HCW × 1,50 and ward occupation ×1,50)

1,50

Assumed

19

Length of patient restriction uptake on the neonatology ward (5 days) and average length of stay of neonates in neonatology ward (14 days)

5 14

Assumed