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Table 1 Serotype distribution of pneumococcal meningitis isolates in Germany among children <16 years, adults ≥16 years, and the overall population (1992/93-2005/06, n = 1382)

From: Pneumococcal meningitis and vaccine effects in the era of conjugate vaccination: results of 20 years of nationwide surveillance in Germany

Serotype

Percent of isolates, children

Percent of isolates, adults

P value

Percent of isolates, overall

No of isolates, overall

14

23.7

7.9

<0.0001

17.5

232

19F

9.3

6.0

0.0260

8.2

108

6B

9.1

5.1

0.0050

7.7

102

18C

8.5

2.8

<0.0001

6.3

83

23F

6.8

8.9

0.1562

8.1

107

7F

6.3

4.6

0.1945

5.8

77

6A

4.4

5.5

0.3783

5.1

67

4

3.5

7.1

0.0028

5.3

70

1

2.8

1.7

0.2063

2.4

32

19A

2.4

3.0

0.6153

2.8

37

3

1.9

7.1

<0.0001

4.4

58

10A

1.8

3.6

0.0406

2.7

36

9V

1.7

5.6

0.0001

3.6

47

8

1.3

3.1

0.0221

2.2

29

33F

1.0

1.7

0.3452

1.4

18

11A

0.9

2.1

0.0686

1.5

20

15B

0.9

1.0

1.0000

1.0

13

9N

0.8

2.3

0.0220

1.5

20

22F

0.6

3.5

0.0002

2.0

26

15C

0.6

0.3

0.4771

0.5

7

23A

0.5

1.7

0.0547

1.1

14

6C

0.5

0.5

1.0000

0.5

7

5

0.5

0.2

0.3934

0.4

5

12F

0.4

1.7

0.0220

1.0

13

17F

0.4

1.0

0.1912

0.7

9

23B

0.3

0.5

0.6588

0.4

5

20

0.3

0.3

1.0000

0.3

4

2

0.1

0.3

0.5845

0.2

3

35B

0.1

0.0

1.0000

0.1

1

others

8.5

10.9

0.1402

10.0

132

  1. Corrected for multiple comparisons using the Dunn-Šidák test (β = 0.001708316).
  2. Significant P values are printed in bold.