|
Case
|
Clinical and laboratory data
|
|---|
|
Age
|
Clinical form
|
Follow-up
|
IIF
|
ELISA
|
ECG
|
ECO (EF%)
|
Chest x-ray
|
Xeno
|
kDNA PCR
|
m.exon PCR
|
|---|
|
1
|
34
|
CF
|
Death
|
1/320
|
1/640
|
PR, PVC
|
Hypokinesia (45)
|
Normal
|
Neg
|
ND
|
ND
|
|
2
|
40
|
CF
|
Death
|
1/640
|
1/1280
|
RBBB, LAHB, PVC, PAC
|
Hypokinesia ↑ LA (35)
|
Cardiomegaly
|
ND
|
ND
|
ND
|
|
3
|
48
|
CF
|
Alive
|
1/1280
|
RI 4.8
|
RBBB, LAHB
|
Normal (75)
|
Normal
|
Neg
|
Neg
|
Neg
|
|
4
|
65
|
CF
|
Death
|
1/320
|
1/640
|
RBBB, LAHB, PVC
|
Delayed relaxation (60)
|
Normal
|
ND
|
ND
|
ND
|
|
5
|
49
|
IF
|
Alive
|
1/320
|
RI 6.6
|
Normal
|
PDA (62)
|
Normal
|
Neg
|
Neg
|
Neg
|
|
6
|
46
|
CF
|
Alive
|
1/640
|
RI 4.0
|
RBBB, LAHB
|
Normal (66)
|
Normal
|
Neg
|
Neg
|
Neg
|
|
7
|
55
|
CF
|
Alive
|
1/640
|
RI 5.0
|
LBBB, PVC
|
Normal (75)
|
Normal
|
Neg
|
Pos
|
Neg
|
|
8
|
57
|
CF/DF
|
Alive
|
1/640
|
RI 4.4
|
RBBB
|
Normal (76)
|
Megaesophagus
|
Pos
|
Neg
|
Neg
|
|
9
|
33
|
CF
|
Alive
|
1/320
|
RI 5.7
|
Primary ST-T changes
|
Hypokinesia ↑ VE (53)
|
Normal
|
Neg
|
Neg
|
Neg
|
|
10
|
41
|
IF
|
Alive
|
1/40
|
RI 2.0
|
Normal
|
Normal (68)
|
Normal
|
Neg
|
Neg
|
Neg
|
|
11
|
50
|
DF
|
Lost to follow- up
|
1/40
|
RI 1.5
|
Normal
|
--
|
Megaesophagus
|
ND
|
ND
|
ND
|
|
12
|
24
|
IF
|
Alive
|
1/80
|
RI 4.1
|
Normal
|
Normal (65)
|
Normal
|
Neg
|
Pos
|
Pos
|
|
13
|
15
|
IF
|
Alive
|
1/160
|
RI 6.2
|
Normal
|
Normal (67)
|
Normal
|
Neg
|
Pos
|
Neg
|
|
14
|
34
|
IF
|
Alive
|
1/160
|
RI 6.4
|
Normal
|
Normal (68)
|
Normal
|
Neg
|
Pos
|
Neg
|
|
15
|
68
|
CF
|
Alive
|
1/80
|
RI 1.1
|
RBBB
|
Delayed relaxation (74)
|
Cardiomegaly
|
Neg
|
Neg
|
Neg
|
- CF = cardiac form, DF = digestive form, ECG = electrocardiography; ECO = echocardiography, EF = ejection fraction, ELISA = enzyme-linked immunosorbent assay, IF = indeterminate form, IIF = indirect immunofluorescence, kDNA = kinetoplast DNA, LA = left atrium, LAHB = left anterior hemiblock, LBBB = left bundle branch block, LV = left ventricle, m.exon = mini-exon multiplex, ND = not determined; PAC = premature atrial complex, PCR = polymerase chain reaction, PDA = patent ductus arteriosus, PVC = premature ventricular complex, PR = pacemaker rhythm, x –ray = radiograph, RBBB = right bundle branch block, RI = reactivity index.
- The ages described are from the beginning of the patients’ follow-up at our outpatient service. Except for cases 1, 2 and 4 who died before the start of this study, all clinical and laboratory data were reevaluated to check for serological and molecular diagnosis and the clinical form presentation. All patients presented negative hemoculture for T. cruzi.
