Skip to main content

Table 3 Characteristics of the episodes of severe sepsis: Sequential data from 2006 to 2011

From: Epidemiology and recent trends of severe sepsis in Spain: a nationwide population-based analysis (2006-2011)

  2006 2007 2008 2009 2010 2011
Men 59.2% (58.7, 59.8) 58.8% (58.3, 59.3) 58.4% (57.9, 58.9) 58.4% (57.9, 58.8) 57.8%(57.3, 58.3) 57.2% (56.8, 57.7)
Age 62.7 ± 0.15 63.9 ± 0.13 64.6 ± 0.12 65.7 ± 0.11 67.0 ± 0.11 67.6 ± 0.10
Men 61.2 ± 0.19 62.6 ± 0.16 63.2 ± 0.16 64.5 ± 0.14 65.9 ± 0.14 66.1 ± 0.13
Women 64.8 ± 0.23 65.7 ± 0.19 66.7 ± 0.17 67.5 ± 0.16 68.5 ± 0.17 69.5 ± 0.16
Age groups       
<18 y 9.7% (9.4, 10.0) 8.6% (8.3, 8.9) 8.1% (7.9, 8.4) 7.3% (7.1, 7.5) 6.6% (6.3, 6.8) 6% (5.8, 6.3)
18-64 y 28.5% (28.0, 29.0) 28.1% (27.6, 28.6) 27.7% (27.3, 28.1) 26.8% (26.4, 27.2) 25.6% (25.2, 26.0) 25.7% (25.3, 26.0)
>64 y 61.8% (61.2, 62.4) 63.3% (62.8, 63.8) 64.2% (63.7, 64.6) 65.9% (65.5, 66.3) 67.8% (67.4, 68.2) 68.3% (67.9, 68.7)
Diagnostic categories       
Medical 75.3% (74.8, 75.8) 75.1%(74.7, 75.6) 72.8%(72.3, 73.2) 73.1% (72.7, 73.5) 74.1% (73.7, 74.5) 74.8% (74.4, 75.2)
Surgical 24.7% (24.2, 25.2) 24.9%(24.4, 25.3) 27.2% (26.8, 27.7) 26.9% (26.5, 27.3) 25.9% (25.5, 26.3) 25.2% (24.8, 25.6)
Charlson index 1.76 ± 0.01 1.73 ± 0.01 1.84 ± 0.01 1.90 ± 0.01 1.91 ± 0.01 1.95 ± 0.01
Comorbidities       
Cancer (non-metastatic) 17.0% (16.6, 17.4) 16.8%(16.4, 17.2) 16.7% (16.3, 17.1) 17% (16.6, 17.4) 17.2% (16.8, 17.5) 17.7% (17.3, 18.0)
COPDa 12.9% (12.5, 13.3) 13.2%(12.8, 13.6) 13.4% (13.1, 13.7) 13.9% (13.6, 14.2) 13.3% (13.0, 13.7) 13.2% (12.9, 13.5)
Chronic cardiac failure 12.5% (12.1, 12.9) 13.1% (12.8, 13.5) 13.9% (13.5, 14.2) 14.6% (14.3, 14.9) 14.9% (14.5, 15.2) 15.4% (15.1, 15.7)
Chronic renal disease 8.8% (8.5, 9.2) 8.8% (8.5, 9.1) 13.3% (13.0, 13.6) 14.9% (14.5, 15.2) 15.4% (15.0, 15.7) 16.1% (15.8, 16.4)
Cerebrovascular 8.4% (8.1, 8.8) 8.1% (7.8, 8.4) 8.3% (8.0, 8.5) 8.4% (8.0, 8.5) 8.4% (8.1, 8.6) 8.3% (8.1, 8.6)
Cancer with metastasis 5.6% (5.3, 5.9) 5.5% (5.3, 5.7) 5.7% (5.4, 5.9) 5.8% (5.6, 6.1) 6.3% (6.1, 6.5) 6.4% (6.2, 6.6)
Number of organ dysfunctions       
1 55.1% (54.5, 55.6) 54.1% (53.6, 54.7) 53.9% (53.4, 54.3) 53.1% (52.6, 53.5) 53.9% (53.4, 54.3) 52.0% (51.6, 52.4)
2 26.8% (26.3, 27.3) 26.2% (25.7, 26.7) 25.9% (25.5, 26.3) 26.1% (25.6, 26.5) 25.5% (25.1. 25.9) 26.4% (26.0, 26.8)
≥3 18.2% (17.7, 18.6) 19.7% (19.3, 20.1) 20.3% (19.9, 20.6) 20.9% (20.5, 21.3) 20.7% (20.3, 21.0) 21.6% (21.3, 22.0)
Type of organ dysfunction b       
Respiratory 51.9% (51.4, 52.5) 52.3% (51.8, 52.8) 51.6% (51.1, 52.1) 51.6% (51.1, 52.0) 48.9% (48.4, 49.4) 47.7% (47.3, 48.1)
Cardiovascular 45.9% (45.3, 46.4) 47.0% (46.5, 47.5) 45.9% (45.4, 46.4) 44.4% (44.0, 44.9) 43.9% (43.4, 44.3) 42.8% (42.3, 43.2)
Renal 36.5% (36.0, 37.1) 37.0% (36.5, 37.6) 38.2% (37.7, 38.6) 40.1% (39.6, 40.5) 41.7% (41.3, 42.2) 46.5% (46.1, 47.0)
Hepatic 5.3% (5.1, 5.6) 5.2% (5.0, 5.5) 5.4% (5.2, 5.7) 5.4% (5.2, 5.7) 5.1% (4.9, 5.3) 4.9% (4.7, 5.1)
Metabolic 7.4% (7.1, 7.7) 7.2% (7.0, 7.5) 7.8% (7.5, 8.0) 8.7% (8.4, 8.9) 8.7% (8.5, 9.0) 9.4% (9.1, 9.6)
Neurologic 10.6% (10.3, 11.0) 10.6% (10.3, 11.0) 10.8% (10.5, 11.1) 11.2% (10.9, 11.5) 11.1% (10.8, 11.4) 11.2% (11.0, 11.5)
Hematolologic 11.1% (10.7, 11.5) 11.0% (10.7, 11.4) 11.8% (11.5, 12.1) 11.8% (11.5, 12.1) 11.9% (11.6, 12.2) 12.4% (12.1, 12.7)
Identified Germs b       
Yes 26.9% (26.4, 27.4) 25.6% (25.1, 26.0) 25.4% (25.0, 25.8) 24.8% (24.4, 25.2) 25.8% (25.4, 26.2) 26.1% (25.8, 26.5)
Gram positive 39.4% (38.4, 40.5) 39.2% (38.2, 40.3) 39.1% (38.2, 40.1) 37.3% (36.4, 38.3) 35.1% (34.3, 36.0) 33.6% (32.8, 34.4)
Gram-negative 56.3% (55.2, 57.4) 56.3% (55.2, 57.3) 58.1% (57.1, 59.0) 59.2% (58.3, 60.1) 62.4% (61.5, 63.3) 64.5% (63.7, 65.4)
Anaerobic 1.5% (1.2, 1.8) 1.5% (1.3, 1.8) 1.4% (1.2, 1.7) 1.7% (1.5, 2.0) 1.5% (1.3, 1.8) 1.8% (1.6, 2.0)
Fungus 9.4% (8.7, 10.0) 8.7% (8.1, 9.3) 7.4% (6.9, 7.9) 7% (6.5, 7.5) 6.8% (6.3, 7.2) 6.1% (5.8, 6.6)
Bacteremia 18% (17.6, 18.5) 16.4% (16.0, 16.8) 16.2% (15.9, 16.6) 16.4% (16.0, 16.7) 16.2% (15.9, 16.6) 16.4% (16.0, 16.7)
Length of stay (days) 24.8 ± 0.19 24.5 ± 0.17 24.1 ± 0.16 23.1 ± 0.14 21.9 ± 0.13 21.0 ± 0.12
Case-fatality 45.4% (44.9, 46.0) 45.9% (45.4, 46.5) 43.6% (43.1, 44.1) 42.9% (42.5, 43.4) 41.5% (41.0, 41.9) 40.2% (39.8. 40.6)
  1. aChronic Obstructive Pulmonary Disease. bProportions not mutually exclusive.
  2. Data presented as % of cases (with its corresponding 95% Confidence Interval) or mean ± SE.