Number of deaths and age-adjusted standardized mortality rates. The data represent, for the entire population of severe sepsis and for men and women in a specific manner, the annual number of deaths (plot 2a) and the age-adjusted standardized mortality rates (plot 2b). Rates were calculated by direct methods based on the European standard population. For the entire population the number of deaths raised from 12988 cases in 2006 to 20012 in 2011, whereas the standardised mortality rate has gone from 32.1 cases in 2006 to 45.3 cases per 100000 population in 2011. In men, the number of deaths increased from 7650 to 11290 and the standardised mortality rate went from 43.76 cases in 2006 to 59.76 cases/100000 population in 2011. In women (5338 deaths in 2006, 8722 in 2011), the increase was higher going from 22.95 cases/100000 population in 2006 to 34 cases/100000 population in 2011 (right section).