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Table 2 Antibiotic susceptibility patterns of typhoidal and non-typhoidal salmonellea recovered from blood cultures

From: Salmonella blood stream infections in a tertiary care setting in Ghana

Antibiotics Proportion of resistant Salmonella species (%)
Total P-value 2010 2011 2012 2013 Correlation coefficient c,d
  TS a NTS b   TS NTS TS NTS TS NTS TS NTS TS NTS
Ampicillin 27/43 (62.7) 81/103 (78.6) 0.0466 12/14 (85.7) 20/23 (83.3) 9/13 (69.2) 28/37 (75.6) 3/13 (23.1) 23/30 (76.6) 3/10 (30.0) 10/13 (76.9) rs = −0.8, P = 0.2 rs = −0.2, P = 0.8
cefuroxime 11/63 (17.4) 21/104 (20.2) 0.6636 4/14 (28.5) 5/20 (25.0)) 4/13 (30.7) 11/38 (28.9) 2/26 (76.9) 4/31 (12.9) 1/10 (10.0) 1/15 (66.7) rs = −0.2, P = 0.8 rs 0.4, P = 0.6
Cefotaxime 0 6/99 (6.1) - 0 1/23 (4.5) 0 3/41 (7.3) 0 2/35 (57.1) 0 0 - rs = −0.2, P = 0.8
Amoxicillin/ Clavulante 1/12 (8.3) 11/20 (55.5) <0.01 NT 2/5 (40.0) NT 6/7 (85.7) 1/12 (8.3) 3/8 (37.5) 0 0 - rs = −0.8, P = 0.2
Gentamicin 1/24 (4.1) 9/91 (9.9) 0.3892 0 2/23 (9.1) 0 5/35 (14.3) 1/24 (4..2) 2/33 (6.6) 0 0 rs = 0.26, P = 0.74 rs = −0.8, P = 0.2
Amikacin 1/11 (9.1) 2/71 (2.8) 0.3025 0 0 0 1/38 (2.6) 0 1/33 (3.3) 1/11 (9.1) 0 rs = 0.77, P = 0.23 rs =0.26, P = 0.75
Chloramphenicol 27/44 (61.4) 66/90 (73.3) 0.1579 10/13 (76.9) 10/19 (52.6) 12/13 (92.3) 25/33 (75.7) 5/18 (27.7) 22/27 (81.5) NT 9/11 (81.8) - rs =1 P = 0.001
Cotrimoxazole 24/174 (13.8) 54/87 (65.5) 0.0002 8/145 (5.5) 10/18 (55.5) 7/13 (53.8) 19/36 (52.7) 8/10 (80.0) 17/21 (80.9) 1/6 (16.7) 8/12 (66.7) rs =0.4, P = 0.6 rs = 0.6, P = 0.4
Tetracycline 26/37 (70.3) 60/83 (72.3) 0.8204 9/14 (64.2) 14/17 (82.3) 9/13 (69.2) 22/32 (68.8) 8/10 (80.0) 16/23 (69.5) 0 8/11 (72.7) rs = −0.2, P = 0.8 rs = −0.2, P = 0.8
Ciprofloxacin 0 1/ 135 (0.7) - 0 0 0 1/135 (0.7) 0 0 0 0 - -
  1. aTS, typhoidal salmonellae; bNTS, non-typhoidal salmonellae; crs, Spearman’s Correlaltion Coefficient, measures the overall significant increase or decrease in antibiotic resistance level over the 4-year period; dP, P-values at <0.05 are significant.
  2. The number of salmonellae tested for susceptibility differ for each antibiotic. Results are thus recorded as proportions (number of resistant strains per total isolates tested for a particular antibiotic) with percentages in parenthesis.