The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a cross-sectional study

Table 2 Cell types and expression of CCR5 and CXCR4 for HIV-infected and uninfected individuals

Cell type	Control	LTNP	HIV	p-value
Total white blood cells, *n (10 ⁶ /L)**	6043	7060	5846	0.214
CD14+ of CD45+ cells	9.0	8.2	10.1	0.186
CD3+ of CD45+ cells	24.7	29.9	30.7	0.188
CD8 + CD3+ of CD45 + cells	7.2	11.5	19.1	0.003
CCR5+	50.6	43.1	57.8	0.161
CXCR4+	92.2	97.4	95.1	0.590
CD4 + CD3+ of CD45 + cells	14.94	16.62	8.99	0.018
CCR5+	22.5	16.9	30.0	0.014
CXCR4+	70.2	83.7	71.9	0.185
CD45RO+ of CD3 + CD4+ cells	49.6	45.6	52.6	0.360
CCR5+	40.1	30.5	44.4	0.065
CXCR4+	45.8	70.6	57.7	0.191
CD45RA+ of CD3 + CD4+ cells	45.4	52.6	44.5	0.396
CCR5+	6.4	8.5	18.6	0.018
CXCR4+	91.6	94.6	90.3	0.595
CD25^highFoxP3+ of CD3 + CD4 + cells	6.5	4.8	5.4	0.091
CCR5+	49.1	41.9	49.4	0.790
CXCR4+	97.9	98.2	95.6	0.712

Data are given as percentage unless stated otherwise.
Groups were compared with Kruskal-Wallis analyses.
HIV: human immunodeficiency virus; LTNP: long-term non-progressors; Control: HIV uninfected healthy controls.

ISSN: 1471-2334