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Table 6 Clinical and autopsy cause of death by month since starting TB treatment for 228 deaths among men with confirmed and probable TB 1 , by HIV status, n (%)

From: Timing, rates, and causes of death in a large South African tuberculosis programme

  HIV negative or unknown HIV positive on ART HIV positive not on ART TOTAL
1st month 2nd-6th month TOTAL 1st month 2nd-6th month TOTAL 1st month 2nd-6th month TOTAL
Clinical Cause of Death
TB 1 (50) 6 (75) 7 (70) 8 (100) 25 (66) 33 (72) 21 (66) 87 (62) 108 (63) 148 (65)
Non-TB natural deaths 1 (50) 2 (25) 3 (30) 0 13 (34) 13 (28) 11 (34) 52 (37) 63 (37) 79 (35)
Unnatural deaths 0 0 0 0 0 0 0 1 (1) 1 (1) 1 (0)
Autopsy Cause of Death
TB 1 (50) 2 (50) 3 (50) 3 (60) 6 (33) 9 (39) 11 (58) 19 (26) 30 (33) 42 (35)
Non-TB natural deaths 1 (50) 2 (50) 3 (50) 2 (40) 12 (67) 14 (61) 8 (42) 54 (73) 61 (66) 78 (64)
Pneumonia    2 2 5 7 1 19 20 29
Pneumocystis pneumonia    0   2 2 2 13 15 17
Cryptococcus    0    0 1 6 7 7
Other infection 2    0   4 4 1 8 9 13
Kaposi’s sarcoma    0    0   1 1 1
Lung cancer    0   1 1 1 1 2 3
Other cancer 1 2 1    0 1 1 2 3
Other medical 3    0    0 1 4 5 5
Unnatural deaths    0    0   1 (1) 1 (1) 1 (1)
No autopsy done 0 4 4 3 20 23 13 67 80 107
  1. 1228 men included 54 treated for the first time and 40 retreated with confirmed TB, and 75 treated for the first time and 59 retreated with probable TB (see Table 1 footnote 1 for definitions used).
  2. 2Includes 12 men with HIV infection not otherwise specified and one with HIV infection and meningitis as the cause of death.
  3. 3Includes three men with stroke, one with diabetes, and one with silicosis as the cause of death.
  4. Italics give numbers of deaths without percentages.