Timing, rates, and causes of death in a large South African tuberculosis programme

BMC Infectious Diseases

Table 6 Clinical and autopsy cause of death by month since starting TB treatment for 228 deaths among men with confirmed and probable TB ¹ , by HIV status, n (%)

	HIV negative or unknown			HIV positive on ART			HIV positive not on ART			TOTAL
	1st month	2nd-6th month	TOTAL	1st month	2nd-6th month	TOTAL	1st month	2nd-6th month	TOTAL	TOTAL
Clinical Cause of Death
TB	1 (50)	6 (75)	7 (70)	8 (100)	25 (66)	33 (72)	21 (66)	87 (62)	108 (63)	148 (65)
Non-TB natural deaths	1 (50)	2 (25)	3 (30)	0	13 (34)	13 (28)	11 (34)	52 (37)	63 (37)	79 (35)
Unnatural deaths	0	0	0	0	0	0	0	1 (1)	1 (1)	1 (0)
Autopsy Cause of Death
TB	1 (50)	2 (50)	3 (50)	3 (60)	6 (33)	9 (39)	11 (58)	19 (26)	30 (33)	42 (35)
Non-TB natural deaths	1 (50)	2 (50)	3 (50)	2 (40)	12 (67)	14 (61)	8 (42)	54 (73)	61 (66)	78 (64)
Pneumonia			2	2	5	7	1	19	20	29
Pneumocystis pneumonia			0		2	2	2	13	15	17
Cryptococcus			0			0	1	6	7	7
Other infection ²			0		4	4	1	8	9	13
Kaposi’s sarcoma			0			0		1	1	1
Lung cancer			0		1	1	1	1	2	3
Other cancer	1	2	1			0	1	1	2	3
Other medical ³			0			0	1	4	5	5
Unnatural deaths			0			0		1 (1)	1 (1)	1 (1)
No autopsy done	0	4	4	3	20	23	13	67	80	107

¹228 men included 54 treated for the first time and 40 retreated with confirmed TB, and 75 treated for the first time and 59 retreated with probable TB (see Table 1 footnote 1 for definitions used).
²Includes 12 men with HIV infection not otherwise specified and one with HIV infection and meningitis as the cause of death.
³Includes three men with stroke, one with diabetes, and one with silicosis as the cause of death.
Italics give numbers of deaths without percentages.

ISSN: 1471-2334