Respiratory syncytial virus infection-associated hospitalization in adults: a retrospective cohort study

BMC Infectious Diseases

Table 2 Complications and outcomes of 86 patients hospitalized with RSV infection, 2012/13 winter season

Complication/outcome	Number (%)
Lower respiratory tract complications¹	45 (52%)
Cardiovascular complications²	19 (22%)
Pneumonia³	34 (40%)
Confirmed radiologically	26 (30%)
Unifocal infiltrate	18 (21%)
Multifocal infiltrates	8 (9%)
Lobar consolidation	11 (13%)
Co-pathogen identified⁴	11 (13%)
Viral⁵	2 (2%)
Bacterial⁶	9 (11%)
Need for intensive care	13 (15%)
Need for invasive mechanical ventilation	8 (9%)
In hospital mortality	5 (6%)
Median time to death (range)	6 days (2–52 days)
Median hospital length of stay (range)	6 days (1–140 days)

¹Lower respiratory tract complications included exacerbation of COPD (n = 11) or asthma (n = 5), or pneumonia (n = 34).
²Cardiovascular complications included new arrhythmia (n = 7), CHF exacerbation (N = 12), myocardial infarction (n = 1), and stroke (n = 2).
³Pneumonia as diagnosed by treating physicians.
⁴Co-pathogen identified in nasopharyngeal swab, sputum or bronchoscopy specimen culture within 5 days of admission. No patients had concomitant bacteremia.
⁵Viral co-pathogens included influenza A (n = 1), and both influenza B and CMV in another patient.
⁶Bacterial co-pathogens included Haemophilus influenzae (n = 3), methicillin-sensitive Staphylococcus aureus (n = 1), Streptococcus pyogenes (n = 1), Streptococcus pneumoniae (n = 2), methicillin-resistant Staphylococcus aureus (n = 1), and Pseudomonas aeruginosa (n = 1).

ISSN: 1471-2334