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Table 1 Demographic and clinical characteristics of HCV-infected patients and healthy control subjects

From: Variations in DEPDC5 gene and its association with chronic hepatitis C virus infection in Saudi Arabia

Variable

Chronic HCV

Liver cirrhosis

HCC

Healthy control

pvalue a

Age (yrs)

50.9 ± 14.98

58.30 ± 11.86

63.23 ± 10.70

30.79 ± 8.90

<0.0001

Male gender (%)

233 (51.4%)

61 (50%)

12 (46.2%)

550 (96.7%)

<0.0001

BMI (Kg/m2)*

29.2 (25.67-33.39)

30.06 (26.22-33.06)

25.99 (21.89-31.39)

 

0.804

Platelets (109/L)*

230 (178.75-282.25)

163.5 (108.50-205.50)

104.00 (51.50-139.00)

 

<0.0001

ALT (U/L)**

68.973 ± 57.99

78.66 ± 50.76

114.33 ± 31.78

 

0.738

AST (U/L)**

43.54 ± 33.30

72.67 ± 48.81

91.33 ± 24.58

 

<0.0001

ALP (U/L)**

113.37 ± 78.91

133.66 ± 90.04

147.00 ± 96.70

 

0.072

DM2

     

Overall (30.8%)

134 (72.4%)

44 (23.8%)

7 (3.8%)

 

0.693

HCV genotypes

     

4 (357)

249 (70%)

86 (24%)

22 (6%)

 

<0.0001

1 (148)

115(77.7%)

30 (20.3%)

3 (2%)

 

Others¶¶ (96)

89 (92.7%)

6 (6.3%)

1 (1%)

 

HCV RNA (Log10)*

5.85 (4.81-6.54)

5.63 (4.86-6.32)

5.98 (2.79-7.24)

 

0.552

  1. *Values are expressed as median interquartile range (25th - 75th), **Values are expressed as mean ± SD.
  2. pa: nonparametric test and one way Anova for continuous data and Chi square test for categorical data.
  3. ¶¶ includes genotypes 2, 3 and untypable genotypes. Abbreviations: HCV hepatitis C virus, HCC hepatocellular carcinoma, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP Alkaline Phosphatase, BMI body mass index; DM2: diabetes mellitus.