Skip to main content

Table 6 Demography, history, and physical parameters of female patients investigated in the safety set

From: Review of the literature and individual patients’ data meta-analysis on efficacy and tolerance of nitroxoline in the treatment of uncomplicated urinary tract infections

 

Nitroxoline

Controls

p-value

Demographic parameter

n

Median (range)

n

Median (range)

 

Age (years)

234

48 (18–89)

232

47 (18–85)

0.520

-up to 45 years

234

113 (48.3%)

232

115 (49.6%)

0.745

Height (cm)

234

165 (150–185)

231

165 (145–187)

0.290

Weight (kg)

234

62 (43–100)

232

64 (42–102)

0.125

Body mass index (kg /m2)

234

23.0 (15.9–41.3)

231

23.2 (15.6–38.0)

0.038

Heart rate (min −1)

231

80 (52–172)

231

80 (56–120)

0.354

Systolic BP (mmHg)

232

120 (80–195)

231

130 (100–190)

0.025

Diastolic BP (mmHg)

232

80 (60–120)

231

80 (50–120)

0.410

No hypertension (SBP ≤ 140 mmHG)

232

165 (71.1%)

231

137 (59.3%)

0.004

Mild hypertension (SBP > 140 mmHG)

232

46 (19.8%)

231

63 (27.3%)

 

Moderate hypertension (SBP > 160 mmHG)

232

17 (7.3%)

231

22 (9.5%)

 

Severe hypertension (SBP > 180 mmHG)

232

4 (1.7%)

231

9 (3.9%)

 

Diabetes mellitus

234

11 (4.7%)

232

6 (2.6%)

0.230

Duration of urinary symptoms (d)

165

3 (1–30)

168

3 (1–21)

0.442

Pretreatment with antimicrobials*

234

16 (6.8%)

232

8 (3.4%)

0.060

Only unspecific pretreatment#

234

25 (10.7%)

232

28 (12.1%)

0.667

  1. *antibiotics, chemotherapeutics.
  2. #spasmolytics, analgetics, tea etc.