From: Diabetes does not affect outcome in patients with Enterobacteriaceae bacteremia
Diabetics n = 181 | Non-diabetics n = 931 | p-value | RR* (95% CI) | |
---|---|---|---|---|
Demographics | ||||
Male | 88 (48.6) | 521 (51.4) | 0.07 | 0.78 (0.59–1.01) |
Age, years (mean ± SD) | 75.4 ± 11.9 | 70 ± 16.6 | <0.001 | - |
Nosocomial | 24 (13.3) | 119 (13) | 0.9 | 1.02 (0.69–1.51) |
ICU-acquired | 1 (0.6) | 10 (1.1) | 1 | 0.55 (0.09–3.6) |
Treated in ICU | 8 (4.4) | 48 (5.2) | 0.42 | 0.87(0.45–1.67) |
Postsurgical | 4 (2.2) | 33 (3.6) | 0.5 | 0.65 (0.26–1.67) |
Severe sepsis or shock | 32 (17.7) | 130 (14) | 0.21 | 1.25 (0.89–1.77) |
Adequate empirical antibiotic | 150 (84.7) | 751 (81.6) | 0.39 | 1.21 (0.83–1.77) |
Blood glucose concentration, mg/dL (mean ± SD) | 236 ± 103 | 143 ± 50 | <0.001 | - |
Comorbidities | ||||
COPD** | 25 (13.8) | 89 (9.6) | 0.12 | 1.4 (0.96–2.03) |
Ictus | 15 (8.3) | 48 (5.2) | 0.11 | 1.5 (0.94–2.38) |
Cirrhosis | 11 (6.1) | 50 (5.4) | 0.72 | 1.11 (0.64–1.93) |
Chronic renal failure | 12 (6.6) | 24 (2.6) | 0.01 | 2.11 (1.31–3.43) |
Immunosuppression | 4 (2.2) | 48 (5.2) | 0.12 | 0.46 (0.18–1.19) |
Cardiac failure | 19 (10.5) | 41 (4.4) | 0.002 | 2.05 (1.38–3.05) |
Origin of infection | ||||
Urinary | 100 (55.9) | 479 (51.9) | 0.37 | 1.14 (0.87–1.5) |
Biliary | 34 (19) | 166 (18) | 0.75 | 1.06 (0.75–1.49) |
Unknown | 24(13.4) | 138 (15) | 0.65 | 0.9 (0.6–1.34) |
Intraabdominal | 7 (3.9) | 52 (5.6) | 0.47 | 0.72 (0.35–1.46) |
Pneumonia | 4 (2.2) | 26 (2.8) | 0.81 | 0.82 (0.33–2.05) |
Microorganism | ||||
E. coli | 135 (74.6) | 726 (78.3) | 0.28 | 0.84 (0.62–1.14) |
Klebsiella spp. | 19 (10.5) | 62 (6.7) | 0.09 | 1.49 (0.98–2.26) |
Other | 27 (14.9) | 139 (15) | 1 | 1 (0.69–1.461 |
Polymicrobial | 20 (11) | 70 (7.6) | 0.14 | 1.41 (0.93–2.12) |
Death | 13 (7.2) | 76 (8.2) | 0.77 | 1.13 (0.67–1.9) |
Length of hospital stay, days (mean ± SD) | 13.3 ± 12 | 13.9 ± 15 | 0.64 |