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Table 3 ROC analysis results.

From: Diagnosing norovirus-associated infectious intestinal disease using viral load

Reference groups used

Optimal Ct cut-off

Youden Index

Sensitivity

(95% CI)

Specificity

(95% CI)

AUC

Sample size

      

Reference positive

Reference negative

Ref positive 1

Ref negative 1

       

All

31

0.77

0.88

(0.65–1.00)

0.89

(0.84–0.94)

0.93

92

159

aged <5 years

30

0.80

0.94

(0.84–1.00)

0.86

(0.79–0.93)

0.93

48

92

aged >5 years

33

0.83

0.89

(0.79–0.98)

0.94

(0.88–1.00)

0.96

44

67

Ref positive 2

       

Ref negative 1

       
 

31

0.61

0.72

(0.66–0.79)

0.89

(0.84–0.94)

0.87

169

159

Ref positive 3

       

Ref negative 2

       
 

31

0.29

0.43

(0.39–0.47)

0.86

(0.77–0.94)

0.64

524

64

  1. The reference groups are described in Table 1. AUC is the area under the curve.
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BMC Infectious Diseases

ISSN: 1471-2334

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