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Table 1 Inclusion criteria for the ROC analysis reference groups

From: Diagnosing norovirus-associated infectious intestinal disease using viral load

Reference group Inclusion Criteria
Reference
positive 1
1. IID
2. Norovirus detected by electron microscopy
3. Norovirus infection confirmed by RT-PCR
Reference
positive 2
1. IID
2. Norovirus detected by electron microscopy
3. Norovirus infection confirmed by RT-PCR
Or
1. IID
2. Electron microscopy negative
3. Norovirus detected by RT-PCR
4. No other pathogen detected
5. Specimen collected within 3 days of symptom onset
Reference
positive 3
1. IID
2. Norovirus detected by electron microscopy and/or RT-PCR
3. Negative for Campylobacter spp., Salmonella spp. and Shigella spp. by bacterial culture and Cryptosporidiumspp. by light microscopy
(and rotavirus A by ELISA in children aged less than five years only)
Reference
negative 1
1. No history of IID in previous 3 weeks
2. Norovirus detected by RT-PCR
Reference
negative 2
1. IID
2. Norovirus detected by RT-PCR
3. Infection with Salmonella spp., Campylobacter spp. or Shigella spp. detected by bacterial culture or Cryptosporidium spp. detected by light microscopy
(or rotavirus A by ELISA in children aged less than five years only)