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Table 1 Characteristics of H. influenzaecases by serotype detected from 2001 to 2005 (n = 192).#

From: Invasive Haemophilus influenzaeinfections in Germany: impact of non-type b serotypes in the post-vaccine era

Number cases/examined cases (% or 10–90th percentile) Type b
N = 64
Non-type b – capsulated
N = 18
Non-type b – uncapsulated
N = 70
Median age at disease onset
(10–90th percentile)
11 (3–40) 31(5–68) 26 (0–73)
Male sex 36/64 (56%) 9/18 (50%) 49/70 (70%)
Diagnosis    
   Meningitis 43/64 (67%) 12/18 (67%) 23/68 (34%)***
   Pneumonia 5/64 (8%) 3/18 (17%) 14/68 (21%)*
   Epiglottitis 6/64 (9%) 0/18 (0%) 0/68 (0%)**
   Septic arthritis 1/64 (2%) 1/18 (6%) 0/68 (0%)
   Osteomyelitis 1/64 (2%) 0/18 (0%) 0/68 (0%)
   Other foci 4/64 (6%) 1/18 (6%) 12/68 (18%)
   Septicaemia without focus 4/64 (6%) 1/18 (6%) 19/68 (28%)*
No underlying disease 56/63 (89%) 14/18 (78%) 40/65 (62%)***
Outcome    
   recovery 48/64 (75%) 13/18 (72%) 52/63 (83%)
   sequelae 12/64 (19%) 4/18 (22%) 9/63 (14%)
   Death 4/64 (6%) 1/18 (6%) 2/63 (3%)
Biotype    
   I 31/45 (69%) 10/17 (59%) 11/70 (16%)***
   II 13/45 (29%) 5/17 (29%) 31/70 (44%)
   III 0/45 (0%) 1/17 (6%) 18/70 (26%)
   IV 0/45 (0%) 1/17 (6%) 0/70 (0%)
   V 0/45 (0%) 0/17 (0%) 8/70 (11%)*
   Other 1/45 (2%) 0/17 (0%) 2/70 (3%)*
  1. # if global tests were significant (p < 0.001), capsulated and uncapsulated non-type b cases were pairwise compared to type b cases (* p < 0.05, ** p < 0.01, *** p < 0.001).