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Table 1 Characteristics of H. influenzaecases by serotype detected from 2001 to 2005 (n = 192).#

From: Invasive Haemophilus influenzaeinfections in Germany: impact of non-type b serotypes in the post-vaccine era

Number cases/examined cases (% or 10–90th percentile)

Type b

N = 64

Non-type b – capsulated

N = 18

Non-type b – uncapsulated

N = 70

Median age at disease onset

(10–90th percentile)

11 (3–40)

31(5–68)

26 (0–73)

Male sex

36/64 (56%)

9/18 (50%)

49/70 (70%)

Diagnosis

   

   Meningitis

43/64 (67%)

12/18 (67%)

23/68 (34%)***

   Pneumonia

5/64 (8%)

3/18 (17%)

14/68 (21%)*

   Epiglottitis

6/64 (9%)

0/18 (0%)

0/68 (0%)**

   Septic arthritis

1/64 (2%)

1/18 (6%)

0/68 (0%)

   Osteomyelitis

1/64 (2%)

0/18 (0%)

0/68 (0%)

   Other foci

4/64 (6%)

1/18 (6%)

12/68 (18%)

   Septicaemia without focus

4/64 (6%)

1/18 (6%)

19/68 (28%)*

No underlying disease

56/63 (89%)

14/18 (78%)

40/65 (62%)***

Outcome

   

   recovery

48/64 (75%)

13/18 (72%)

52/63 (83%)

   sequelae

12/64 (19%)

4/18 (22%)

9/63 (14%)

   Death

4/64 (6%)

1/18 (6%)

2/63 (3%)

Biotype

   

   I

31/45 (69%)

10/17 (59%)

11/70 (16%)***

   II

13/45 (29%)

5/17 (29%)

31/70 (44%)

   III

0/45 (0%)

1/17 (6%)

18/70 (26%)

   IV

0/45 (0%)

1/17 (6%)

0/70 (0%)

   V

0/45 (0%)

0/17 (0%)

8/70 (11%)*

   Other

1/45 (2%)

0/17 (0%)

2/70 (3%)*

  1. # if global tests were significant (p < 0.001), capsulated and uncapsulated non-type b cases were pairwise compared to type b cases (* p < 0.05, ** p < 0.01, *** p < 0.001).