Table 4 Operating characteristics of TST and LPA assays for the diagnosis of active TB.
|  | All subjects | Subjects with TST ≥ 5 mm | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | Sensitivity, % | Specificity, % | AUROC | PPV | NPV | Sensitivity, % | Specificity, % | AUROC | PPV | NPV |
TST | 84.6 | 65.5 | 0.7507 | 1.7 | 99.8 | -- | -- | -- | -- | -- |
ESAT-6 | 38.5 | 92.0 | 0.6516 | 3.2 | 99.5 | 45.5 | 86.8 | 0.6611 | 5.6 | 98.9 |
Ag85 | 46.2 | 91.5 | 0.6882 | 3.68 | 99.6 | 54.6 | 81.3 | 0.6790 | 4.8 | 99 |
WCL | 61.5 | 73.0 | 0.6728 | 1.58 | 99.6 | 72.7 | 54.3 | 0.6353 | 2.68 | 99.1 |