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Table 1 Baseline characteristics of trial participants

From: High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial

 

Intention-to-treat (ITT) analysis

Modified ITT analysis

 

NTZ

Placebo

NTZ

Placebo

Number of children

30

30

26

26

Sex (M:F)

14:16

20:10

13:13

18:8

Age (months)

20 (11.3)

21 (20.2)

21 (11.9)

22 (17.8)

CD4 count (cells/μL)

579 (378)

614 (403)

583 (316)

503 (394)

Weight (kg) (mean, SD)

7.2 (1.8)

7.3 (2.0)

7.3 (2.0)

7.3 (2.0)

Presence of oedema (number, %)

6 (20)

5 (17)

5(19)

4 (15)

Hb (g/dL) (mean, SD)

[range]

8.7 (2.2)

[4.9-12.8]

8.3 (1.8)

[4.5-13.1]

8.3 (1.8)

[5.8-11.9]

8.2 (2.0)

[4.5-13.1]

WBC (×109/L)

11.6 (6.2)

[4.7-35]

11.0 (5.1)

[3.2-21.9]

12.5 (6.7)

[5.2-35]

10.9 (5.1)

[4.7-13.1]

Na+ (mmol/L)

137.2 (2.5)

137.6 (1.9)

137.3 (3.3)

138.3 (1.0)

K+ (mmol/L)

4.4 (0.5)

4.4 (0.5)

4.5 (0.6)

4.5 (0.5)

Creatinine (μmol/L)

95.5 (39.2)

89.1 (38.3)

95.6 (34.8)

92.4 (38.2)

Alkaline phosphatase (i.u./l)

148 (72)

164 (69)

151 (77)

168 (61)

AST (i.u./l)

62.1 (61)

61 (22)

54 (23)

64 (22)

ALT (i.u./l)

45 (30)

48 (25)

45 (30)

48 (26)

  1. Values shown are mean (SD) unless otherwise specified; where shown, values in square brackets represent range. Statistical testing using the t test or Fisher's exact test showed no significant differences between NTZ and placebo groups by either ITT or PP analysis.