Figure 1

Time evolution of the virological parameters for STI subjects. Plasma viremia, CD4⁺ T cell and CD8 T cell response are plotted for three subjects of the cohort data. They were started on long courses of HAART within the first six months of primary infection (from left to right 3, 2 and 1.5 years, respectively). Then, they were enrolled in a structured interruption protocol (arm B). The therapy resumption was required for a viral load ≥ 50,000 copies/ml (dashed line). The shaded area indicates the reinstitution of therapy. They managed to control viremia after the initial treatment interruption for at least one month.