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Table 3 Characteristics of children receiving ART (n = 54)

From: Barriers to the care of HIV-infected children in rural Zambia: a cross-sectional analysis

 

At clinic enrollment

At ART initiationa

At study enrollment

Median age (yrs) (IQR)

3.6 (1.5, 7.7)

3.8 (2.0, 8.0)

4.5 (2.7, 8.6)

Median WAZ (IQR) b

-2.7 (-3.5, -1.5)

-2.5 (-3.9, -1.8)

-2.4 (-3.2, -1.5)

   WAZ <-2

27 (61.4)

28 (70.0)

26 (60.5)

   WAZ ≥-2

17 (38.6)

12 (30.0)

17 (39.5)

Median CD4 + T cell % (IQR)

14.0 (9.2, 19.0)

12.4 (9.2, 18.6)

28.6 (23.5, 36.1)

Median CD4 + T cell count (IQR)

505 (281, 985)

368 (219, 559)

973 (466, 1522)

   Severe immunodeficiencyc

16 (50)

24 (63)

2 (5)

Median total lymphocyte count (IQR)

3194 (1948, 5351)

2747 (1634, 5351)

3372 (1862, 5276)

Median hemoglobin (IQR)

10.6 (10.0, 11.7)

10.8 (10.0, 12.0)

11.9 (10.6, 12.3)

   Hemoglobin <8 gm/dL

1 (2.0)

0 (0)

4 (8.9)

   Hemoglobin ≥8 gm/dL

49 (98.0)

36 (100.0)

41 (91.1)

WHO stage

   

   1

2 (5.1)

2 (7.1)

6 (17.7)

   2

9 (23.1)

1 (3.6)

6 (17.7)

   3

22 (56.4)

20 (71.4)

20 (58.8)

   4

6 (15.4)

5 (17.9)

2 (5.9)

ART regimen

   

   AZT/3TC/EFV

---

12 (26.1)

11 (42.3)

   AZT/3TC/NVP

---

11 (23.9)

7 (26.9)

   d4T/3TC/EFV

---

5 (10.8)

2 (7.7)

   d4T/3TC/NVP

---

18 (39.1)

6 (23.1)

  1. ART = antiretroviral therapy; IQR = interquartile range; WAZ = weight-for-age Z score; WHO = World Health Organization; AZT = zidovudine; 3TC = lamivudine; EFV = efavirenz; NVP = nevirapine; d4T = stavudine
  2. a7 children transferred to Macha and had already initiated ART
  3. bfor children <10 yrs old
  4. csevere immunodeficiency defined by age according to WHO guidelines