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Table 4 Dichotomous variables; association with QFT-G results in tuberculosis patients

From: Use of a T cell interferon gamma release assay in the investigation for suspected active tuberculosis in a low prevalence area

  QFT positive QFT negative Odds ratio 95% CI interval p-value
Male 14 14 2.70 0.96 – 7.62 0.0504
Female 27 10    
Origin from high or intermediate TB incidence country* 33 16 2.04 0.63 – 6.66 0.1710
Origin from low incidence country 8 8    
Born abroad and lived <5 years in Sweden 14 5 1.95 0.61 – 6.96 0.1970
Born in, or lived >5 years in, Sweden 27 19    
Extra pulmonary tuberculosis 19 4 4.31 1.25 – 14.87 0.0142
Pulmonary tuberculosis 22 20    
Sputum smear negative** 9 6 1.62 0.38 – 7.15 0.4666
Sputum smear positive 13 14    
Immunosuppressed patients *** 9 8 1.76 0.55 – 5.58 0.2357
Immune-competent patients 32 16    
TST ≥ 10 mm 27 9 3.00 0.37 – 24.50 0.3000
TST < 10 mm 2 2    
  1. QFT: QuantiFERON®-TB Gold; CI: Confidence Interval; BMI: Body Mass Index (kg/m2); TST: Tuberculin skin test
  2. 5 patients with indeterminate results excluded
  3. * High or moderate TB-incidence is defined as ≥20 cases/100 000 population
  4. ** For pulmonary TB only (result missing in 2 patients)
  5. *** Immune suppression defined as HIV-infection, ongoing immunosuppressive treatment, cancer, diabetes, alcohol or drug abuse