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Table 1 Characterization (antibiogram, PCR-RFLP of the coagulase gene and PFGE) of low and high-level mupirocin resistant S. aureus isolated in Nigeria and South Africa

From: Phenotypic and molecular characterization of Staphylococcus aureus isolates expressing low- and high-level mupirocin resistance in Nigeria and South Africa

Strain No Antibacterial
resistance patterns
MUP MIC
(mg/L)
mupA
gene
Coagulase gene
(± 20 bp)
PCR-RFLP Coagulase
gene (bp)
PFGE
type
A1 PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Hg 12 - 800 324, 405 A
A2 PEN, OX, GN, TET, TS, RF, MU (L) 24 - 650 81, 567 B
A3 PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb 16 - 850 324, 405 A
A4 PEN, OX, GN, TET, TS, RF, MU (L), Cad, Hg 24 - 650 81, 567 B
A5 PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb 12 - 800 324, 405 A1
A6 PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb 8 - 800 81, 324, 405 A
A7 PEN, OX, GN, ERY, TET, TS, RF, MU (L), Cad 24 - 650 81, 567 B1
A8 PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb 8 - 800 81, 324, 405 A
A9 PEN, OX, GN, ERY, TET, TS, RF, MU (L), Cad, Hg 24 - 650 81, 567 B2
A10 PEN, OX, GN, ERY, CHL, TET, TS, CIP, MU (L), Hg 12 - 800 81, 324, 405 A
A11 PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb 8 - 800 81, 324, 405 A
A12 PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Hg 12 - 850 81, 324, 405 A2
A13 PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Hg 8 - 800 81, 324, 405 A1
A14 PEN, OX, GN, ERY, TET, TS, CIP, MU (L), Cad, Pi, Hg, Eb 12 - 800 81, 324, 405 A
A15 PEN, OX, GN, ERY, TET, TS, RF, MU (H), Cad >1024 + 650 81, 567 B3
P1929 TM, TET, MU (H), Cad >1024 + 750 243, 486 C
35 IBA TET, MU (H), Cad >1024 + 800 81, 162, 567 D
  1. KEY. PEN – Penicillin, OX – Oxacillin, GN – Gentamicin, ERY – Erythromycin, CHL – Chloramphenicol,
  2. TET – Tetracycline, TS – Trimethoprim, RF – Rifamipicin, CIP – Ciprofloxacin,
  3. MU (H) – High-level mupirocin resistance, MU (L) – Low-level mupirocin resistance
  4. Heavy metals – Cad: Cadmium acetate; Hg: Mercuric chloride Nucleic acid binding compounds – Eb: Ethidium bromide; Pi: Propamidine isethionate