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Table 2 Interferon-gamma (IFN-γ) responses (TB antigen, PHA and nil) in blood (n = 29) and pleural fluid (n = 32)a)

From: Evaluation of immune responses in HIV infected patients with pleural tuberculosis by the QuantiFERON®TB-Gold interferon-gamma assay

 

TB antigens

Positive control (PHA)

Negative control (nil)

Blood (IU/ml)

   

   Confirmed TB pleuritis (n = 12)

1.20 (0.11–11.80)be

1.24 (0.11–15.00)

0.22 (0.05–2.06)

   Probable TB pleuritis (n = 12)

3.97 (0.32–11.05)be

0.50 (0.10–4.00)c

0.22 (0.07–1.62)

   Non-TB pleuritis (n = 5)

0.13 (0.08–0.31)

15.00 (1.23–15.00)

0.10 (0.07–0.18)

Pleural fluid (IU/1 × 10 6 PFMCs)

   

   Confirmed TB pleuritis (n = 16)

14.40 (2.15–169.00)

11.45 (1.85–81.20)

8.90 (2.10–55.60)d

   Probable TB pleuritis (n = 11)

19.18 (1.31–143.90)be

16.60 (0.95–118.00)

15.23 (0.87–103.00)b

   Non-TB pleuritis (n = 5)

1.10 (0.13–7.30)

4.60 (2.20–9.00)

0.70 (0.14–8.80)

  1. Data are presented as medians. The ranges are listed in brackets. PFMC = pleural fluid mononuclear cells.
  2. a) It was not possible to obtain blood from five patients and pleural fluid from two patients.
  3. b) p < 0.01, c) p = 0.02, d) p = 0.03 compared with the 'non-TB group'. e) p < 0.01 compared with negative control.
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BMC Infectious Diseases

ISSN: 1471-2334

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