Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children

BMC Infectious Diseases

Table 3 Variability and predictors of co-receptor affinity per study group.

	Cases	Controls	p
Available for testing	29/45 (64%)	30/41(73%)	0.38
PCR failed	0/29	1/30	1.00
Complete env product	25/29	26/29	1.00
Degenerate base counts (median, range)	2 (0–21)	4 (0–36)	0.33
Viral type C	29/29	28/29	1.00
V3 amino acid charge ≥ +5*	0/25	4/27	0.11
X4 strains (C-PSSM)*	2/25	2/27	1.00

Presence of several indicators of co-receptor affinity in children with severe anaemia (cases, Hb<5.0 g/dL) as compared to those without severe anaemia (controls). * according to C-PSSM score by Jensen [25], available at [45].

ISSN: 1471-2334