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Table 3 Variability and predictors of co-receptor affinity per study group.

From: Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children

  Cases Controls p
Available for testing 29/45 (64%) 30/41(73%) 0.38
PCR failed 0/29 1/30 1.00
Complete env product 25/29 26/29 1.00
Degenerate base counts (median, range) 2 (0–21) 4 (0–36) 0.33
Viral type C 29/29 28/29 1.00
   V3 amino acid charge ≥ +5* 0/25 4/27 0.11
   X4 strains (C-PSSM)* 2/25 2/27 1.00
  1. Presence of several indicators of co-receptor affinity in children with severe anaemia (cases, Hb<5.0 g/dL) as compared to those without severe anaemia (controls). * according to C-PSSM score by Jensen [25], available at [45].