|
Parameter
|
Month
|
IFN gamma
|
Placebo
|
p (Student's t)
|
|---|
|
Oxidative stress
| |
N = 10
|
N = 8
| |
|---|
|
SOD (U/mL/min)
|
0
|
36.2 ± 17.8
|
27.2 ± 11.5
|
0.23
|
| |
6
|
28.6 ± 12.6
|
29.8 ± 16.5
|
0.85
|
| |
P (6 vs 0)
|
0.034
|
0.612
| |
|
AOPP (μM)
|
0
|
71.3 ± 35.2
|
60.8 ± 34.5
|
0.46
|
| |
6
|
48.4 ± 15.2
|
65.7 ± 27.6
|
0.12
|
| |
P (6 vs 0)
|
0.008
|
0.734
| |
|
Genetic modulation (relative to GAPDH × 100)
| |
N = 8
|
N = 6
| |
|
TGF beta
|
0
|
113 ± 37
|
113 ± 29
|
0.99
|
| |
6
|
152 ± 106
|
235 ± 232
|
0.80
|
| |
p (6 vs 0)
|
0.401
|
0.028
| |
|
TNF alpha
|
0
|
37 ± 35
|
68 ± 21
|
0.080
|
| |
6
|
37 ± 34
|
81 ± 28
|
0.025
|
| |
p (6 vs 0)
|
0.946
|
0.370
| |
|
MCP-1
|
0
|
112 ± 58
|
38 ± 29
|
0.015
|
| |
6
|
59 ± 27
|
69 ± 39
|
0.60
|
| |
p (6 vs 0)
|
0.032
|
0.244
| |
- Data are expressed as mean ± SD.
- Analyses within groups were performed by the Student's paired t test.
