Adjuvant interferon gamma in patients with pulmonary atypical Mycobacteriosis: A randomized, double-blind, placebo-controlled study

BMC Infectious Diseases

Table 5 Molecular expression and oxidative stress studies.

Parameter	Month	IFN gamma	Placebo	p (Student's t)
Oxidative stress		N = 10	N = 8
SOD (U/mL/min)	0	36.2 ± 17.8	27.2 ± 11.5	0.23
	6	28.6 ± 12.6	29.8 ± 16.5	0.85
	P (6 vs 0)	0.034	0.612
AOPP (μM)	0	71.3 ± 35.2	60.8 ± 34.5	0.46
	6	48.4 ± 15.2	65.7 ± 27.6	0.12
	P (6 vs 0)	0.008	0.734
Genetic modulation (relative to GAPDH × 100)		N = 8	N = 6
TGF beta	0	113 ± 37	113 ± 29	0.99
	6	152 ± 106	235 ± 232	0.80
	p (6 vs 0)	0.401	0.028
TNF alpha	0	37 ± 35	68 ± 21	0.080
	6	37 ± 34	81 ± 28	0.025
	p (6 vs 0)	0.946	0.370
MCP-1	0	112 ± 58	38 ± 29	0.015
	6	59 ± 27	69 ± 39	0.60
	p (6 vs 0)	0.032	0.244