Effect of treating Schistosoma haematobium infection on Plasmodium falciparum-specific antibody responses

BMC Infectious Diseases

Table 2 Results of the Factor Analysis using Principle Components giving the loadings of each antibody response in each component.

	Principle Component 1 (anti-plasmodial responses)	Principle Component 2 (anti-schistosome responses)
Initial Eigen values % variance	46.465	13.241
Variables	Loadings	Loadings
WWH-IgG1	0.08	0.796
WWH-IgG3	-0.011	0.879
MSP-2 (CH150)-IgG1	0.864	-0.064
MSP-2 (CH150)-IgG3	0.715	0.101
MSP-2 (Dd2)-IgG1	0.740	-0.001
MSP-2 (Dd2)-IgG3	0.857	-0.30
MSP-1 (DPK)-IgG1	0.615	-0.304
MSP-1 (DPK)-IgG3	0.662	0.216
MSP-1 (MSP1₁₉)-IgG1	0.682	-0.2
MSP-1 (MSP1₁₉)-IgG3	0.876	-0.043
Schizont-IgG1	0.697	0.028
Schisont-IgG3	0.704	0.211

Principle Component 1 (PCA1) is most influenced by the anti-plasmodial responses while PCA2 is most influenced by anti-schistosome responses. The loadings indicate the correlation between the original variable and the new principle competent (PC), i.e. they indicate the extent to which the original variables are influential in forming the PC [32]. Variables with loadings > 0.5 are highlighted in bold.

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