Skip to main content

Table 1 Characteristics of HIV-infected patients with Pneumocystis pneumonia according to HAART status on admission.

From: Outcome of HIV-associated Pneumocystis pneumonia in hospitalized patients from 2000 through 2003

Characteristic

All (n = 292)

Not on HAART (n = 178)

On HAART (n = 107)

Age, median years, (range)

40 (23–68)

40 (23–63)

41 (21–68)

Gender, n (%)

   

Male

246 (84.2)

152 (85.4)

90 (84.1)

Female

46 (15.8)

26 (14.6)

17 (15.9)

Race/ethnicity, n (%)

   

White

30 (10.3)

17 (9.6)

12 (11.2)

Black

102 (34.9)

63 (35.4)

37 (34.6)

Hispanic/Latino

151 (51.7)

91 (51.1)

57 (53.3)

Other/unknown

9 (3.1)

7 (3.9)

1 (0.9)

HIV risk factor, n (%)

   

Men who have sex with men

97 (33.2)

58 (32.6)

38 (35.5)

Intravenous drug use

32 (11.0)

18 (10.1)

13 (12.1)

Heterosexual

80 (27.4)

50 (28.1)

29 (27.1)

Blood transfusion

3 (1.0)

1 (0.6)

2 (1.9)

Unknown

80 (27.4)

51 (28.7)

25 (23.4)

Medical history, n (%)

   

Initial HIV diagnosis

80 (27.4)

79 (44.4)

0 (0)*

History of PCP

72 (24.7)

26 (14.6)

43 (40.2)*

Use of PCP prophylaxis

92 (31.5)

30 (16.9)

60 (56.1)*

Use of HAART

107 (36.6)

0 (0)

107 (100)*

Current smoker

116 (39.7)

74 (41.6)

41 (38.3)

Laboratory values

   

CD4, cells/μl, median (range)(n = 131)

19 (0–697)

18 (1–267)

22 (0–697)

HIV viral level, log copies/ml, median (range)(n = 57)

5.3 (1.7–5.9)

5.3 (1.7–5.9)

5.3 (2.6–5.9)

Albumin, g/dl, median (range)

2.5 (0.6–4.1)

2.5 (0.6–3.8)

2.4 (0.6–4.1)

LDH, U/l, median (range)

332 (119–1425)

331 (119–1425)

323 (119–962)

Alveolar-arterial oxygen gradient, mm Hg, median (range)(n = 129)

43.3 (18.0–89.0)

44.6 (18.0–89.0)

38.5 (21.8–73.0)

Complications, n (%)

   

ICU admission

100 (34.2)

66 (37.1)

29 (27.1)

Mechanical ventilation

39 (13.4)

25 (14.0)

11 (10.3)

Pneumothorax

20 (6.8)

17 (9.6)

2 (1.9)^

Respiratory failure after 5 days

10 (3.4)

8 (4.5)

2 (1.9)

Change of PCP therapy

14 (4.8)

10 (5.6)

4 (3.7)

Outcome

   

Died in-hospital

34 (11.6)

21 (11.8)

10 (9.3)

Length of stay, median days (range)

8 (1–89)

9 (1–89)

6 (2–69)*

  1. Abbreviations: HAART, highly active antiretroviral therapy; ICU, intensive care unit; LDH, lactate dehydrogenase; PCP, Pneumocystis pneumonia.
  2. Note: HAART use was unavailable for 7 subjects.
  3. *p ≤ 0.001
  4. ^p = 0.01
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us