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Table 4 Factors predicting in-hospitala mortality and mortality within 1 year from admission in 326 episodes of infective endocarditis

From: Short-term and one-year outcome of infective endocarditis in adult patients treated in a Finnish teaching hospital during 1980–2004

  Hazard ratio for in-hospital death 95% CI p value Hazard ratio for death within 1 year 95% CI p value
Age    0.068    0.005
   18–64 years 1    1   
   ≥65 years 1.72 1.0–3.03   2.17 1.27–3.70  
Sex    0.426    0.707
   Female 1    1   
   Male 1.32 0.67–2.60   1.12 0.61–2.10  
Etiology    0.060b    0.066b
   Staphylococcus aureus 1    1   
   CoNSc 0.87 0.33–2.26   0.93 0.36–2.40  
   Viridans streptococci 0.90 0.40–2.03   0.85 0.40–1.81  
   Enterococcus faecalis 0.36 0.08–1.57   0.55 0.16–1.90  
   Streptococcus pneumoniae 2.37 0.85–6.59   2.58 0.94–7.09  
   Other pathogens 0.35 0.08–1.54   0.31 0.07–1.36  
   Culture negative 0.42 0.17–1.05   0.51 0.23–1.13  
Affected valves    <0.001b    <0.001b
   Prosthetic 1    1   
   Aortic 1.13 0.48–2.65   1.01 0.46–2.19  
   Mitral 0.45 0.16–1.31   0.60 0.24–1.47  
   Tricuspid 1.04 0.22–4.88   0.73 0.16–3.35  
   Two native valves 3.55 1.49–8.47   3.75 1 68–8.34  
Echocardiography       
   Major Criterion    0.346    0.015
No 1    1   
Yes 1.43 0. 68–3.00   2.44 0.19–5.0  
   Vegetation    0.102    0.005
No 1.    1   
Yes 1.81 0.90–3.68   2.62 1.35–5.09  
Neurological complications d    0.009    0.003
No 1    1   
Yes 2.17 1.21–3.90   2.30 1.34–3.96  
Peripheral emboli d    0.036    0.016
No 1    1   
Yes 1.86 1.04–3.33   1.95 1.14–3.35  
Heart failure d    <0.001    <0.001
No 1    1   
Yes 5.98 2.35–15.17   7.62 3.26–17.83  
Serum CRP on admission    0.008    <0.001
   < 100 mg/l 1    1   
   ≥100 mg/l 2.92 1.33–6.40   3.90 1.81–8.43  
  1. aMean (SD) duration of in-hospital treatment was 55 (33), range 4 to 272 days; bp values for overall group differences; ccoagulase-negative staphylococci; dwithin 3 months from admission