Skip to main content

Table 3 Association between in-hospitala complications and clinical characteristics in 326 episodes of infective endocarditis

From: Short-term and one-year outcome of infective endocarditis in adult patients treated in a Finnish teaching hospital during 1980–2004

  N Neurologic events n (%) p value Cerebral emboli n (%) p value Peripheral emboli n (%) p value Heart failure n (%) p value
Sex    0.404   0.297   0.354   0.538
   Male 234 65 (27.8)   38 (16.2)   77 (32.9)   125 (53.4)  
   Female 92 21 (22.8)   10 (10.9)   25 (27.2)   53 (57.6)  
Age    0.695   1.0   0.619   0.037
   18–64 years 209 57 (27.3)   31 (14.8)   63 (30.1)   105 (50.2)  
   ≥65 years 117 29 (24.8)   17 (14.5)   39 (33.3)   73 (62.4)  
Etiology    0.035b   0.182b   <0.001c   0.019b
   Staphylococcus aureus 75 26 (34.7)   14 (18.7)   39 (52.0)   37 (49.3)  
   CoNSc 31 7 (22.6)   5 (16.1)   3 (9.7)   20 (64.5)  
   Viridans streptococci 67 18 (26.9)   15 (22.4)   20 (29.9)   28 (41.8)  
   Enterococcus faecalis 25 6 (24.0)   2 (8.0)   7 (28.0)   17 (68.0)  
   Streptococcus pneumoniae 11 7 (63.6)   2 (18.2)   3 (27.3)   10 (90.9)  
   Other pathogens 28 6 (21.4)   2 (7.1)   9 (32.1)   14 (50.0)  
   Negative 89 16 (18.0)   8 (9.0)   21 (23.6)   52.(58.4)  
Affected valves    0.170b   0.105b   <0.001b   0.002b
   Aortic 113 30 (26.6)   16 (14.2)   43 (38.1)   64 (56.6)  
   Mitral 96 25 (26.0)   17 (17.7)   24 (25.0)   46 (47.9)  
   Tricuspid 18 3 (16.7)   0 (0)   10 (55.6)   4 (22.2)  
   Two native valves 32 14 (43.8)   8 (25.0)   18 (56.3)   25 (78.1)  
   Prosthetic valve(s) 67 19 (20.9)   7 (10.5)   7 (10.5)   39 (58.2)  
Echocardiography          
   Major criterion    0.504   1.0   0.055   0.057
Yes 221 61 (27.6)   33 (14.9)   77 (34.8)   129 (58.4)  
No 105 25 (23.8)   15 (14.3)   25 (23.8)   49 (46.7)  
   Vegetation    0.158   0.425   <0.001   0.088
Yes 198 58 (29.3)   32 (16.2)   76 (38.4)   116 (58.6)  
No 128 28 (21.9)   16 (12.5)   26 (20.37)   62 (48.4)  
Intravenous drug use    1.0   1.0   0.012   0.146
Yes 25 6 (24.0)   3 (12.0)   14 (56.0)   10 (40.0)  
No 301 80 (26.6)   45 (15.0)   88 (29.2)   168 (55.8)  
  1. aMean (SD) duration of in-hospital treatment was 55 (33), range 4 to 272 days; bp values for overall group differences; ccoagulase-negative staphylococci