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Table 4 Total, median, and mean acquisition cost of antifungals (US Dollars)

From: Antifungal prophylaxis in chemotherapy-associated neutropenia: a retrospective, observational study

  AMB Period (n = 255)1 AZ Period (n = 317)1
  n2 Total Cost3 Median Cost4 Mean Cost4 n2 Total Cost3 Median Cost4 Mean Cost4
AMB 254 $119,194 $70 ($65–$76) $467 ($274–$661) 198 $36,129 $18 ($9–$27) $113 ($40–$186)
FLU 33 $8,343 0 $29 ($2–$56) 228 $78,849 $173 ($108–$224) $245 ($211–$278)
VOR 4 $10,485 0 $34 ($0–$76) 160 $216,559 $75 (0–$250) $682 ($563–$802)
CASPO 7 $17,228 0 $66 ($11–$122) 43 $174,718 0 $537 ($333–$741)
ITRA 50 $7,984 0 $29 ($19–$40) 6 $833 0 $3 ($0–$5)
Total 348 $164,405 $70 $630 645 $507,175 $266 $1,577
  1. 1Number of hospitalizations with available charges
  2. 2Number of hospitalizations with charges for the individual antifungals
  3. 3All costs are rounded to the nearest dollar
  4. 4Median or mean cost (lower 95% confidence interval to upper 95% confidence interval). Reported means are least squared means from mixed effects regression models that controlled for the number of hospitalizations
  5. Note: AMB = amphotericin; AZ = Azole; FLU = fluconazole; VOR = voriconazole; CASPO = caspofungin; ITRA = itraconazole