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Figure 1 | BMC Infectious Diseases

Figure 1

From: Adjuvant TACE inhibitor treatment improves the outcome of TLR2-/-mice with experimental pneumococcal meningitis

Figure 1

A) Percentage of wt (n = 40), TLR2-/-(n = 35), CD14-/- (n = 29) and TLR2-/-/CD14-/- (n = 31) mice showing high severity score (including score higher than 2.5) after infection with S. pneumoniae. Mean ± SD of four independent experiments (p < 0.02, ANOVA). B) Mortality from untreated pneumococcal meningitis: wt (n = 33), TLR2-/- (n = 24), CD14-/- (n = 21) and TLR2-/-/CD14-/- (n = 10) mice. C) Effect of antibiotic treatment in wt (n = 15), TLR2-/- (n = 15), CD14-/- (n = 9) and TLR2-/-/CD14-/- (n = 9) mice. Arrow indicates start of ceftriaxone therapy.

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