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Table 3 Intrathoracic disease manifestations on chest radiograph based on HIV status in children with culture-confirmed tuberculosis

From: Culture-confirmed childhood tuberculosis in Cape Town, South Africa: a review of 596 cases

Intrathoracic disease manifestationb

All childrena n = 555 (%)

HIV-uninfected n = 274 (%)

HIV-infected n = 126 (%)

HIV unknown n = 155 (%)

Lymphadenopathy (all)

288 (51.9)

142 (51.8)

71 (56.3)

75 (48.4)

   Paratracheal only

18 (3.2)

9

5

4

   Perihilar only

192 (34.6)

91

46

55

   Both

78 (14.1)

42

20

16

Large airway compression

97 (17.5)

54 (19.7)

17 (13.5)

26 (16.8)

Perihilar opacification

38 (6.8)

15 (5.5)

8 (6.3)

15 (9.7)

Alveolar opacification lobe/segment e

285 (51.4)

128 (46.7)

84 (66.7)

73 (47.1)

Bronchopneumonic opacification

55 (9.9)

28 (10.2)

12 (9.5)

15 (9.7)

Collapse lobe/segment

52 (9.4)

23 (8.4)

14 (11.1)

15 (9.7)

All cavities/breakdownf

106 (19.1)

44 (16.1)

33 (26.2)

29 (18.7)

Pleural effusion (all)

83 (15.0)

37 (13.5)

17 (13.5)

29 (18.7)

   Large effusions

29 (5.2)

9 (3.3)

5 (4.0)

15 (9.7)c

Pericardial effusion

11 (2.0)

6 (2.1)

3 (2.3)

2 (1.1)

Miliary picture

69 (12.4)

44 (16.1)

19 (15.1) d

6 (3.9)

Ghon focus

26 (4.7)

18 (6.6)

3 (2.4)

5 (3.2)

Hyperinflation

15 (2.7)

6 (2.2)

5 (4.0)

4 (2.6)

Calcification

13 (2.3)

4 (1.5)

4 (3.2)

5 (3.2)

Normal chest radiographg

53 (9.5)

32 (11.7)

5 (4.0)

16 (10.3)

  1. a: 41 chest radiographs not done (extrapulmonary TB) or lost
  2. b: In case of uncertainty about a characteristic, it is reported as not present
  3. c: Older children had more large effusions and were less often HIV tested.
  4. d: A further 8 patients had lymphoid interstitial pneumonitis
  5. e: HIV-uninfected vs. HIV-infected group: odds ratio 0.44 (95% confidence interval 0.28–0.70)
  6. f: HIV-uninfected vs. HIV-infected group: OR 0.54 (95% CI 0.31–0.93)
  7. g: HIV-uninfected vs. HIV-infected group: OR 3.20 (95% CI 1.15–9.60)