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Table 1 Particulars of 27 blood culture-positive candidemia patients and results on detection of species-specific Candida DNA, (1,3)-beta-D-glucan, mannan and anti-mannan antibodies by diagnostic kit cut-off value

From: Comparative evaluation of (1, 3)-β-D-glucan, mannan and anti-mannan antibodies, and Candidaspecies-specific snPCR in patients with candidemia

Case no

Age/sex

Underlying condition

Blood culture

Semi-nested PCR with serum

BDG (pg/ml)

Mannan (ng/ml)

Anti-mannan Abs (AU/ml)

1

88/F

Septicemia, Chest infection

C. albicans

C. albicans, C. parapsilosis

35

0.32

9.8

1b*

88/F

Septicemia, Chest infection

C albicans

C. albicans

53

0.32

11.2

2

49/F

Chronic renal failure

C. albicans

C. albicans

40

0.26

0.8

3

79/M

Large bowel obstruction

C. albicans

C. albicans

172

0.8

13.2

4

17/M

Aseptic meningitis

C. albicans

C. albicans

20

0.28

2.4

5

34/M

Gut surgery

C. albicans

C. albicans

130

0.66

6.8

6

50/M

Pancytopenia

C. albicans

C. albicans, C. parapsilosis

30

0.52

0.8

7

56/M

Appendicular mass

C. albicans

C. albicans

44

1.3

10.6

7b*

56/M

Appendicular mass

C albicans

C. parapsilosis

69

0.38

9.6

8

35/M

-

C. albicans

C. tropicalis

131

0.86

20.6

9

42/M

-

C. albicans

C. albicans

43

0.5

3

10

26/F

Small bowel obstruction, pancreatitis

C. albicans

C. albicans, C. parapsilosis

32

0.48

8

10b*

26/F

Small bowel obstruction, pancreatitis

C. albicans

-ve

21

0.22

34

11

22/F

-

C. albicans

-ve

48

0.36

24.4

12

78/F

Laparotomy

C. albicans

-ve

28

0.3

20.8

12b*

78/F

Laparotomy

C. albicans

-ve

22

0.34

27.8

13

71/F

Laparotomy

C. albicans

C. albicans, C. tropicalis

127

1.44

2

14

9mo/F

Pneumonia

C. albicans

C. parapsilosis

112

3.19

1

15

68/M

Bladder cancer

C. albicans

C. parapsilosis

157

0.36

35

16

58/M

Renal failure

C. albicans

C. albicans

254

1.54

7

17

77/M

Chest trauma

C. albicans

C. albicans

97

0.64

1.6

18

48/M

Bronchopneumonia

C. albicans

C. albicans

321

0.24

23.8

19

20/F

Meningitis

C. parapsilosis

C. albicans

32

0.34

11.2

20

80/M

Urinary tract infection

C. parapsilosis

C. parapsilosis

120

0.3

19.4

21

54/F

Diabetes mellitus, LVF

C. parapsilosis

C. parapsilosis

65

0.22

1.4

22

04/M

Head injury

C. parapsilosis

C. albicans

20

0.28

2.2

23

6mo/F

Pneumonia

C. parapsilosis

C. parapsilosis

101

0.62

2.2

24

80/M

Chest infection

C. tropicalis

C. tropicalis, C. albicans, C. parapsilosis

47

0.48

7

25

41/M

Polyarteritis nodusa

C. tropicalis

C. tropicalis

115

2.8

1.4

25b*

41/M

Polyarteritis nodusa

C. tropicalis

C. tropicalis

108

0.4

19.4

26

74/M

Jaundice, fever

C. tropicalis

C. parapsilosis

205

1.88

12.4

27

28/M

Thrombocytopenia

C. kruseii

C. albicans

132

0.2

13.4

  1. Age is expressed in years unless indicated. mo: months, LVF: left ventricular failure, BAL: broncho-alveolar lavage, M: male, F: female, * repeated specimen of the respective patient, – : not grown/information not available
  2. Interpretation of results:
  3. Mannan Ag: positive = > 0.5 ng/ml, intermediate = 0.25–0.5 ng/ml, negative = < 0.25 ng/ml; Anti-mannan antibodies: positive = > 10 AU/ml, intermediate = 5–10 AU/ml, negative = < 5 AU/ml; BDG: positive = = 80 pg/ml, equivocal = > 60 < 80 pg/ml, negative = < 60 pg/ml; positive results are shown in bold letters
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BMC Infectious Diseases

ISSN: 1471-2334

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