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Table 1 Comparison of HIV-1-Seropositive Women with Low (≤ 85 μg/l) versus Normal (>85 μg/l) Serum Selenium Concentrations.

From: Low serum albumin and the acute phase response predict low serum selenium in HIV-1 infected women

  Mean (± SD) or Number (%) Multivariate Logistic Regression1
  Low serum selenium
(n = 104)
Normal serum selenium
(n = 296)
p-value2 Adjusted Odds Ratio (95% CI) p-value
CD4 count (cells/μl) 216 (± 182) 300 (± 210) <0.001 0.90 (0.77, 1.06)3 0.2
Plasma HIV-1 RNA (log10 of copies/ml) 5.6 (± 0.9) 5.3 (± 1.0) 0.01 0.84 (0.61, 1.17) 0.3
Serum albumin (g/dl) 2.86 (± 0.75) 3.34 (± 0.68) <0.001 0.93 (0.90, 0.97) <0.001
Acute phase response4 73 (70%) 129 (44%) <0.001 1.83 (1.05, 3.18) 0.03
HIV-1 symptoms5 83 (80%) 198 (67%) 0.008 - -
HIV-1 signs6 34 (33%) 57 (19%) 0.01 - -
Body mass index (kg/m2) 21.5 (± 3.5) 22.3 (± 4.7) 0.08 - -
  1. SD – standard deviation; CI – confidence interval
  2. 1 CD4 count, plasma HIV-1 RNA, serum albumin were modeled as continuous variables, and the acute phase response was modeled as a dichotomous variable.
  3. 2 Calculated by using t-tests for continuous variables and χ2 tests for dichotomous variables.
  4. 3 Odds ratio is per 100 CD4 cells/μl increase.
  5. 4 The presence of C-reactive protein ≥ 1 mg/dl and/or α1-acid glycoprotein ≥ 100 mg/dl.
  6. 5 Defined as fever for ≥ 1 month, diarrhea for ≥ 1 month, cough for ≥ 1 month, unintended weight loss of ≥ 5 kg during previous year, or itching skin rash during previous year.
  7. 6 Defined as the presence of oral thrush, oral hairy leukoplakia, oral ulcer, maculopapular rash, or Kaposi's sarcoma.