Table 3 Pre & Post-vaccination mean of IL-4, IL-10 and IFN-γ levels with PHA stimulation at various stages in different groups.
|  | Stimulated mean ± SD pg/ml | Statistical analysis | ||||
|---|---|---|---|---|---|---|
IL-4 | Baseline (B) | Before 2nd dose (C) | After 2nd dose (D) | Before 3rd dose (E) | After 3rd dose (F) | Â |
Group IA | 81 ± 82 | 95 ± 130 | 82 ± 55 | 70 ± 51 | 81 ± 92 | B/C p > 0.05 B/D p > 0.05 B/E p > 0.05 B/F p > 0.05 |
Group IB | 63 ± 69 | 38 ± 29 | 48 ± 28 | 58 ± 62 | 87 ± 146 | B/C p > 0.05 B/D p > 0.05 B/E p > 0.05 B/F p > 0.05 |
Group II | 41 ± 72 | 284 ± 232* | 185 ± 159* | 172 ± 151* | 810 ± 203* | B/C p < 0.01* B/D p < 0.01* B/E p < 0.01 * B/F p < 0.01* |
IL-10 | ||||||
Group IA | 162 ± 152 | 118 ± 94 | 155 ± 148 | 160 ± 184 | 188 ± 194 | B/C p > 0.05 B/D p > 0.05 B/E p > 0.05 B/F p > 0.05 |
Group IB | 117 ± 141 | 70 ± 66 | 92 ± 75 | 138 ± 112 | 139 ± 99 | B/C p > 0.05 B/D p > 0.05 B/E p > 0.05 B/F p > 0.05 |
Group II | 295 ± 151 | 365 ± 213 | 231 ± 223 | 229 ± 226* | 302 ± 232* | B/C p < 0.05* B/D p < 0.05* B/E p < 0.05 * B/F p < 0.05* |
IFN-γ | ||||||
Group IA | 107 ± 106 | 125 ± 208 | 133 ± 173 | 246 ± 255* | 274 ± 268* | B/C p > 0.05 B/D p > 0.05 B/E p < 0.01* B/F p < 0.01* |
Group IB | 72 ± 86 | 62 ± 131 | 39 ± 41 | 154 ± 221* | 197 ± 285* | B/C p > 0.05 B/D p > 0.05 D/E p < 0.05* D/F p < 0.05* |
Group II | 348 ± 216 | 408 ± 247 | 292 ± 236 | 409 ± 304 | 273 ± 213 | B/C p > 0.05 B/D p > 0.05 B/E p > 0.05 B/F p > 0.05 |