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Table 1 Leukocytes counts of female Udea:ICR(CD-1) mice at baseline and after treatment with a low-dose cyclophosphamide regimen. Total number of leukocytes (cells/mm3) and differential count in peripheral blood of 10 mice at baseline in day 1 (8 hours prior to first dose), at day 4 (8 hours prior to second dose), during immunosupression (days 5–7), and at recovery (day 11), compared with reference values for 6 week-old mice.

From: Neutropenia induced in outbred mice by a simplified low-dose cyclophosphamide regimen: characterization and applicability to diverse experimental models of infectious diseases

White blood-cell Population

Cells/mm3 (± SEM)

Normal Range

 

Day 1

Day 4

Day 5

Day 6

Day 7

Day 11

 

Total Leukocytes

5155 (405)

845 (104)

370 (84)

610 (94)

620 (179)

5863 (1103)

1000–5000

Neutrophils

528 (50)

0 (0)

10 (10)

0 (0)

36 (31)

1700 (321)

110–2150

Lymphocytes

4256 (395)

831 (100)

337 (72)

517 (95)

419 (124)

2905 (415)

500–4300

Monocytes

371 (74)

14 (7)

14 (9)

93 (29)

166 (76)

1248 (604)

10–300