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Table 1 Comparison of MIC-values as determined for Atopobium vaginae by Ferris et al. [8] and Geißdörfer et al. [24] and in this study.

From: Antibiotic susceptibility of Atopobium vaginae

 

This study

Geißdörfer et al. [24] a

Ferris et al. [8] b

Number of strains

9

1

3

Antimicrobial agent

MIC50 c

Rangec

MICc

Rangec

Ampicillin

0.023

< 0.016 – 0.94

0.032

 

Ampicillin/sulbactam

   

0.06 – 0.25

Azitromycin

< 0.016

< 0.016 – 0.32

  

Bacitracin

3

1 – 4

  

Cefoxitin

  

2

2

Ceftriaxone

   

0.5 – 2

Cefuroxime

0.125

0.016 – 0.25

0.19

 

Ciprofloxacin

0.064

0.023 – 0.25

  

Clindamycin

< 0.016

< 0.016

 

< 0.015

Colistin

> 1024

> 1024

  

Doxycyclin

0.38

0.19 – 0.75

  

Imipenem

  

0.016

< 0.015 – 0.5

Kanamycin

12

8 – 16

  

Linezolid

0.047

0.016 – 0.125

 

0.06 – 0.25

Meropenem

   

< 0.015 – 0.5

Metronidazole

8

2 - > 256

>16

> 32

Moxifloxacin

   

0.06 – 1

Nalidixic acid

> 256

> 256

  

Penicillin

0.094

0.008 – 0.25

0.125

 

Rifampicin

< 0.002

< 0.002

  

Trovafloxacin

   

< 0.015 – 2

Vancomycin

1.5

1 – 4

  
  1. Legend
  2. a. Tested with Etest and agar dilution method.
  3. b. Tested with broth microdilution method for anaerobic bacteria with Brucella Broth supplemented with vitamin K (1 μg/ml), hemin (5 μg/ml) and laked horse blood (5%).
  4. c. Data in μg/ml.