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Table 1 Clinical Characteristics of enrolled subjects by genotype (N = 266).

From: Asymptomatic bacteriuria in sickle cell disease: a cross-sectional study

Clinical characteristics HbSS N = 148 HbSC N = 85 HbSβ0 N = 6 HbSβ+ N = 22 Sickle variants* N = 5
Age yr 26.4 ± 2.6 27 ± 2.3 25.9 ± 2.3 26.5 ± 2.5 25.1 ± 2.5
†Gender (M:F) 71:77 38:47 2:4 13:9 4:1
#Creatinine μmol/L 45.7 ± 9.4a 63.3 ± 11.7b 70.7 ± 23.1b 61.9 ± 12.4b 62 ± 20.4a
#Uric Acid mmol/L 0.3 ± 0.1a 0.3 ± 0.1a 0.4 ± 0.1a 0.4 ± 0.3b 0.3 ± 0.1a
#Haemoglobin g/L 80.2 ± 9.9a 108.2 ± 8b 91.6 ± 11.8b 109.9 ± 12.4b 124 ± 22.1b
#Nucleated Blood cells × 109/Lc 15.9 ± 3.2a 10.2 ± 2.9b 13.3 ± 2.2b 9.2 ± 2.7b 9.9 ± 2.5b
†Proteinuria ≥ trace : No proteinuria (n = 182) 17 7 0 1 0
†Positive History of gram negative sepsis 2 2 0 0 0
†Positive recorded history of ever having UTI 50 25 2 1 1
  1. Values are means ± sd ; † values are counts. Abbreviations – HbSS = Homozygous sickle cell disease, HbSC= Sickle cell-haemoglobin C, HbSβ0 = Sickle cell-β0 thalassemia, HbSβ+ = Sickle cell-β+ thalassemia; UTI= Urinary Tract Infections.
  2. * Sickle variants include sickle cell-hereditary persistence of foetal haemoglobin, sickle cell -haemoglobin O Arab, sickle cell -haemoglobin Lepore-Boston.
  3. # Significant difference in mean values by genotype. Dissimilar superscript to HbSS values are significantly different (p < 0.03)