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Table 1 Consensus categories and their significance according to the algorithms used in the comparison.

From: DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes

 

Algorithms

Category

DR_SEQAN

Retrogram

ANRS

HIVDB

RegaInst

S (green)

Virus expected to be

susceptible to the drug

The corresponding drug can

be used (susceptible)

Susceptible

Potential low-level resistance

(or susceptible)

Susceptible

I (yellow)

Partial/low-level resistance

Consider the use of this drug

if no 'S' class drugs are available

Possible resistance

Intermediate/low-level resistance

Intermediate resistant

IR (orange)

Significant resistance predicted

Consider the use of this drug if no

'S' or 'I' class drugs are available

   

R (red)

Predicted resistance levels

are very high

To be used only if 'S', 'I' or 'IR'

classes are not available

Resistance

High-level resistance

Resistant