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Table 1 Clinical characteristics

From: A prospective study comparing quantitative Cytomegalovirus (CMV) polymerase chain reaction in plasma and pp65 antigenemia assay in monitoring patients after allogeneic stem cell transplantation

Characteristics

Value

Patients

38

Age, y

 

   Median

41

   Range

(11–68)

Sex

 

   Male

22

   Female

16

Diagnosis

 

   Acute leukemia

16

   Lymphoma

6

   Multiple myeloma

4

   Myelodyspastic syndrome

4

   Solid tumor

4

   Non neoplastic disorders

3

   Chronic lynphocytid leukemia

1

Acute GVHD

 

   0–I

27

   II–IV

11

Total body irradiation

 

   Yes

15

   No

23

Conditioning regimen

 

   Standard

25

   Reduced intensity conditioning

13

Type of transplant

 

   Related

30

   Unrelated

8

Hemopoietic reconstitution

 

   Median days of PMN >0.5 × 109/L (range)

16 (11 – 41)

   Median days of PLTS >20 × 109/L (range)

15 (9 – 65)

   Median days of PLTS >50 × 109/L (range)

18 (11 – 88)

Source of stem cells

 

   Peripheral blood

31

   Bone marrow

4

   Cord blood

3

Prophylaxis of aGVHD

 

   CyA+MTX

25

   CyA+MMF

6

   CyA+PDN

4

   Other

3

CMV status (donor/recipient)

 

   Positive/positive

26

   Negative/positive

10

   Positive/negative

2

Deaths

4

  1. GVHD: Graft versus host disease; CyA: Cyclosporin-A; MTX: Methotrexate; PDN: Prednisone; CMV: Cytomeglovirus. MMF: Micofenolate Mofetil; PMN: Peripheral Mononuclear cells; PLTS: Platelets