Skip to main content

Table 2 Characteristics of antibiotic prophylaxis administration

From: Risk of surgical site infection and efficacy of antibiotic prophylaxis: a cohort study of appendectomy patients in Thailand

Characteristics Number % Infection Rate*
Antibiotic prophylaxis (N = 2139)
   No 167 7.8 5 3.0
   Yes 1972 92.2 21 1.1
Time of first antibiotic dose administration (N = 1972)
   >1 hour preoperatively 1004 50.9 8 0.8
   ≤ 1 hour preoperatively 767 38.9 9 1.2
   Intraoperatively 47 2.4 0 0.0
   Postoperatively 154 7.8 4 2.6
Antibiotic agent (N = 1972)
   Combination Metronidazole and Gentamicin 1266 64.2 13 1.0
Single dose combination 766 38.8 8 1.0
Combination within 1 day 130 6.6 1 0.8
Combination > 1 day 370 18.8 4 1.1
   Others** 706 35.8 8 1.1
Single dose 108 5.5 2 1.9
Multiple dose or combination within 1 day 155 7.9 1 0.6
Combination > 1 day 443 22.4 5 1.1
Duration of antibiotic prophylaxis*** (N = 2139)
   None 167 7.8 5 3.0
   1 day 1159 54.2 12 1.0
   >1 day 813 38.0 9 1.1
  1. * Rate = infections/100 operations
  2. ** Others: Penicillin, amoxicillin, amoxicillin/clavulanate, ampicillin, cloxacillin, cefazolin, cephalexin, cefotaxime, ceftriaxone, ceftazidime, cefdinir, cefoxitin, ofloxacin, norfloxacin, cotrimoxazole, chloramphenical, fosfomycin, clindamycin, and amikacin.
  3. *** Median = 1 day (interquartile range 1–2 days)