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Table 1 Demographic features and risk factors associated with seroprevalence of Hepatitis B in children

From: Hepatitis B and C: prevalence and risk factors associated with seropositivity among children in Karachi, Pakistan

 

Hepatitis B virus

  

Risk Factor

Positive n (%)

Negative n (%)

Odds Ratio (OR) 95% confidence interval (CI)

P value

Therapeutic Injections

    

   Yes

45 (69.2)

1766 (50.9)

  

   No

20 (30.8)

1702 (49.1)

2.2 (1.3 – 3.6)

0.003

Use of new needle & and syringe

    

   Yes

44 (67.7)

1694 (48.8)

  

   No

21 (32.3)

1774 (51.2)

2.2 (1.3 – 3.7)

0.003

No: of Injections in the last year

    

   <2 injections

4 (12.5)

371 (28.2)

Reference

 

   2–5 injections

13 (40.7)

462 (35.2)

2.6 (0.8 – 8.1)

 

   >5 injections

15 (46.8)

481 (36.6)

2.9 (1.0 – 852)

0.140

Received Blood Transfusion

    

   Yes

1 (1.5)

51 (1.5)

  

   No

64 (98.5)

3417 (98.5)

1.0 (0.1 – 7.7)

0.964

Hospitalized

    

   Yes

16 (24.6)

590 (17)

  

   No

49 (75.4)

2878(83)

1.6 (0.9 – 12.8)

0.107

Family member died of Liver disease

    

   Yes

7(10.8)

361 (10.4)

  

   No

58 (89.2)

3107 (89.6)

1.0 (0.5 – 2.3)

0.925

Diagnosis in Family member

    

   HCV

1 (14.3)

12 (3.2)

  

   HBV

1 (14.3)

36 (10)

-

 

   Jaundice

5 (71.4)

306 (84.8)

  

   Liver disease

0

7 (2)

 

0.433

Sharing of various items with infected person

    

   Yes

4 (57.1)

110 (31)

  

   No

3 (42.9)

244 (69)

3.0 (0.7 – 13.4)

0.147

Previous Immunization

    

   Vaccinated

54 (83)

3001(86.5)

  

   Non-Vaccinated

11 (7)

467 (13.5)

1.3 (0.7 – 2.5)

0.419

Place vaccinated

    

   Private Sector

7 (10.8)

1030 (29.7)

Reference

 

   Govt. Sector

46 (70.7)

1974 (57)

3.4 (1.5 – 7.6)

 

   None

12 (18.5)

464 (13.3)

3.8 (1.5 – 9.7)

0.022

Visit to Barber Shop

    

   Yes

47 (72.3)

2814 (81.1)

  

   No

18 (27.7)

654 (18.9)

0.6 (0.4 – 1.1)

0.072

Received cuts at Barber Shop

    

   Yes

11 (23.4)

686 (24.4)

  

   No

36 (76.6)

2128 (75.6)

0.9 (0.5 – 1.9)

0.877

Child's ear/nose pierced

    

   Yes

22 (33.8)

1293 (37.3)

  

   No

43 (66.2)

2175 (62.7)

0.9 (0.5 – 1.4)

0.570

Dental treatment

    

   Yes

0

107 (3)

  

   No

65 (100)

3361 (97)

-

0.150

Father education status

    

   Educated

34 (52.3)

2300 (66.3)

  

   Non-Educated

31 (47.7)

1168 (33.7)

1.8 (1.1 – 2.9)

0.018

Mother education status

    

   Educated

25 (38.5)

1964 (56.6)

  

   Non-Educated

40 (61.5)

1504 (43.4)

2.1 (1.3 – 3.5)

0.003

Ethnic Origin

    

   Sindhi

1 (1.5)

86 (2.5)

Reference

 

   Balochi

12 (18.5)

133 (3.9)

7.8 (1.0 – 60.8)

 

   Punjabi

10 (15.4)

996 (28.8)

0.9 (0.1 – 6.8)

< 0.001

   Pathan

4 (6.2)

179 (5)

1.9 (0.2 – 17.5)

 

   Mohajirs

19 (29.2)

1796 (51.8)

0.9 (0.1 – 6.9)

 

   Others

19 (29.2)

278 (8)

5.3 (0.7 – 40.1)

 

Age Group (years)

    

   ≤ 5 years

17 (26.2)

915 (26.4)

Reference

 

   6 – 9 years

14 (21.5)

931 (26.8)

0.8 (0.4 – 1.7)

 

   10 – 13 years

16 (24.6)

934 (27)

0.9 (0.5 – 1.8)

 

   > 13 years

18 (27.7)

688 (19.8)

1.4 (0.7 – 2.8)

0.428

Gender

    

   Boys

38 (58.5)

1788 (51.6)

  

   Girls

27 (41.5)

1680 (48.4)

1.3 (0.8 – 2.2)

0.270