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Table 1 Patient characteristics and outcomes, stratified by polymicrobial infection.

From: Comparison of the systemic inflammatory response syndrome between monomicrobial and polymicrobial Pseudomonas aeruginosa nosocomial bloodstream infections

VARIABLES Polymicrobial (n = 21) Monomicrobial (n = 77) P
  N % N %  
Demographic characteristics      
Age >60 years 7 33.3 29 37.7 0.71
Male gender 17 81.0 46 59.7 0.72
Mean LOS prior to nBSI (days) ± SD (range) 26 ± 28.6 (5–121) - 33 ± 44.7 (2–323) - 0.38
Mean hospital stay (days) ± SD (range) 46.9 ± 32.0 (9–128) - 69.0 ± 75.4 (5–415) - 0.05
ICU stay 19 90.5 63 81.8 0.51
Underlying conditions      
Charlson score ≥3 4 19.0 23 29.9 0.32
Burn injury 9 42.9 8 10.4 0.002
Diabetes mellitus 5 23.8 17 22.1 1.0
Neoplasia 1 4.8 19 24.7 0.064
Neutropenia 0 - 10 13.0 0.11
Gastrointestinal diseases 4 19.0 16 20.8 1.0
Therapeutics      
Mechanical ventilation 15 71.4 47 61.0 0.38
Central venous line 19 90.5 64 83.1 0.51
Hemodialysis 3 14.3 12 15.6 1.0
TPN 3 14.3 21 27.3 0.22
Transfusion 8 38.1 20 26.0 0.28
Prior antibiotics 18 85.7 65 84.4 0.88
Conditions related to the clinical course      
APACHE II score ≥20 at BSI onset 15 71.4 50 64.9 0.58
Mean time to appropriate antimicrobial therapy (days) 3.40 - 1.7 - 0.029
Inadequate antibiotic therapy 18 85.7 37 48.1 0.002
Imipenem resistant P. aeruginosa 6 28.6 20 26.0 0.81
Outcomes      
Respiratory failure 15 71.4 58 75.3 0.72
Cardiovascular failure 7 33.3 30 39.0 0.64
Renal failure 11 52.4 28 36.4 0.18
Hematologic failure 6 28.6 26 33.8 0.65
Hepatic failure 2 9.5 10 13.0 1.0
7-day mortality 6 28.6 16 20.8 0.56
Overall mortality 8 38.1 37 48.1 0.42